| Basic Information | |
|---|---|
| Species | Eucalyptus grandis |
| Cazyme ID | Eucgr.A02861.1 |
| Family | GH29 |
| Protein Properties | Length: 485 Molecular Weight: 54276.2 Isoelectric Point: 7.4512 |
| Chromosome | Chromosome/Scaffold: 1 Start: 39071621 End: 39074457 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 35 | 334 | 0 |
| SQLKWQQREIIMFFHFGVNTFTDSEWGTGHEDPAIFNPVGLNANQWVSAAADAGISLVILTAKHHDGFCLWPSKYTDHSVESSHWKGGKGDVVREFVDAA KAHGVDAGLYLSPWDRHEPRYGHSLEYNEFYLAQLQELLTKYESVREIWFDGAKGSNAPNMTYYFTEWFSMVKELQSSINIFSDAGPDVRWVGNENGSAG TTSWATINGTALSIGNASIERYLSTGDPRGTDYIPPECDVSIRKGWFWHKSQSPKRLSELLQIYYNSVGRNCVMLLNVPPNTTGLISETDVHRLKELRNA | |||
| Full Sequence |
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| Protein Sequence Length: 485 Download |
| MQSCNIYIIN KIIKKSLTKR VPTPPLPILP LPSYSQLKWQ QREIIMFFHF GVNTFTDSEW 60 GTGHEDPAIF NPVGLNANQW VSAAADAGIS LVILTAKHHD GFCLWPSKYT DHSVESSHWK 120 GGKGDVVREF VDAAKAHGVD AGLYLSPWDR HEPRYGHSLE YNEFYLAQLQ ELLTKYESVR 180 EIWFDGAKGS NAPNMTYYFT EWFSMVKELQ SSINIFSDAG PDVRWVGNEN GSAGTTSWAT 240 INGTALSIGN ASIERYLSTG DPRGTDYIPP ECDVSIRKGW FWHKSQSPKR LSELLQIYYN 300 SVGRNCVMLL NVPPNTTGLI SETDVHRLKE LRNALDTIFS VNLAERCSVK ASSRRGGKDG 360 GFGPENVLDS DHLWTYWAPG DKDDDKDRWI EIRGAAGGLR FNVIRVQEAV GLGQRIGRHE 420 IYVDGKKVVQ GTTVGYKRLH RLEGGVVSGS VVRVRITESK GLPLVSSIGL HLDPYWQPKD 480 GNWF* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 3.0e-30 | 46 | 331 | 322 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 3.0e-34 | 70 | 331 | 283 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 4.0e-58 | 36 | 470 | 450 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 35 | 482 | 22 | 466 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 17 | 479 | 1 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 4 | 480 | 6 | 484 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 4 | 480 | 6 | 485 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 33 | 478 | 40 | 483 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 27 | 471 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 27 | 471 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 32 | 466 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 32 | 466 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 32 | 466 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| ES596238 | 291 | 141 | 427 | 0 |
| CX044171 | 294 | 128 | 420 | 0 |
| HE642643 | 293 | 33 | 323 | 0 |
| EY198039 | 319 | 161 | 477 | 0 |
| CO118382 | 256 | 34 | 286 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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