| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si029623m |
| Family | GH29 |
| Protein Properties | Length: 494 Molecular Weight: 54099.8 Isoelectric Point: 6.3988 |
| Chromosome | Chromosome/Scaffold: 2 Start: 37661319 End: 37663482 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 45 | 344 | 0 |
| AAQLRWQRREVIMFFHFGMNTFTDSEWGTGSEDPSLFRPEALDAAQWMDAARAAGASLAILVAKHHDGFCLWPSAYTAHSVRASPWRAGRGDVVREFVGA ARARGVDAGIYLSPWDRHDERYGDEVAYNEYYEAQLHELLTGYGSVSEIWFDGAKGKNATNMTYHFQEWFQTVKQLQRSINIFSDDGPDVRWVGDEKGFA GTTCWSTVNRSMITIGEAGIEKYLNEGDPRGPDWVPPECDVSIRPGWFWHRNETAKPLSQLLEIYYNSVGRNCVLLLNAPPNSTGLVEDADVARLREFGA | |||
| Full Sequence |
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| Protein Sequence Length: 494 Download |
| MAAGPLLSLA AAALAVAILV PTPEAWRPTT PATPPPLPVL PIPSAAQLRW QRREVIMFFH 60 FGMNTFTDSE WGTGSEDPSL FRPEALDAAQ WMDAARAAGA SLAILVAKHH DGFCLWPSAY 120 TAHSVRASPW RAGRGDVVRE FVGAARARGV DAGIYLSPWD RHDERYGDEV AYNEYYEAQL 180 HELLTGYGSV SEIWFDGAKG KNATNMTYHF QEWFQTVKQL QRSINIFSDD GPDVRWVGDE 240 KGFAGTTCWS TVNRSMITIG EAGIEKYLNE GDPRGPDWVP PECDVSIRPG WFWHRNETAK 300 PLSQLLEIYY NSVGRNCVLL LNAPPNSTGL VEDADVARLR EFGAAVATIF GTDLAAGSAA 360 RASSERGGPG GGFAARNVLD GCDDTYWAPT AEDGRRNGYW IELRRPPEAA NRPFNVVRIQ 420 EHVALGQRVE RHEVYVDGAP VANGTTVGHK RLHRLPRAVA GRAVRIWITA RRGPPLLSAV 480 GLHHDPFVEA GAM* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 1.0e-14 | 108 | 344 | 253 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 5.0e-17 | 108 | 353 | 272 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 2.0e-43 | 47 | 354 | 318 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABG73453.1 | 0 | 45 | 493 | 42 | 496 | glycosyl hydrolase family 29 [Oryza brachyantha] |
| GenBank | ACR35251.1 | 0 | 3 | 493 | 2 | 485 | unknown [Zea mays] |
| GenBank | EEC84898.1 | 0 | 45 | 491 | 45 | 491 | hypothetical protein OsI_32076 [Oryza sativa Indica Group] |
| RefSeq | NP_001151568.1 | 0 | 3 | 493 | 2 | 485 | alpha-L-fucosidase 1 [Zea mays] |
| RefSeq | XP_002462685.1 | 0 | 3 | 493 | 2 | 486 | hypothetical protein SORBIDRAFT_02g030220 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3mo4_B | 0 | 43 | 478 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 43 | 478 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 43 | 478 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 43 | 478 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3uet_B | 0 | 43 | 478 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
