| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS016 | Acb1 | cyclic oligonucleotide-based antiphage signaling system (CBASS) | CLAN015 | T4 of E. coli | PMID:35395152 | Acb1 rapidly degrades the CBASS signals 3′3′-cGAMP, cUA and cAAA, but does not cleave cGG. |