APIS family ID | APIS016 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Inhibited defense system | cyclic oligonucleotide-based antiphage signaling system (CBASS) | |||||||||||||
CLAN ID | CLAN019 | |||||||||||||
Seed protein property |
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Phage property |
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PMID/References | PMID:35395152 | |||||||||||||
PDB structures | 7T26; | |||||||||||||
Pfam domains | ||||||||||||||
Phrog | phrog_755 | |||||||||||||
Host taxa | d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia;s__Escherichia coli | |||||||||||||
Gene Location | Start: 73952; End: 74410; Strand: - | |||||||||||||
Description | Acb1 rapidly degrades the CBASS signals 3′3′-cGAMP, cUA and cAAA, but does not cleave cGG. |
Genome accession | Start | End | Strand | Protein ID | Length | Molecular weight | Charge | Isoelectric point | Function | Phrog | PFAM |
---|---|---|---|---|---|---|---|---|---|---|---|
NC_000866.4 | 71253 | 71918 | - | NP_049745.2 | 221 | 26073.77 | 14.5 | 10.0776 | homing endonuclease | phrog_7168 ; phrog_19446 ; phrog_37840 ; phrog_447 ; phrog_15209 ; phrog_314 | PF01541.27 |
NC_000866.4 | 72628 | 72915 | - | NP_049746.1 | 95 | 11153.69 | -3.0 | 4.8667 | hypothetical protein | phrog_2023 | |
NC_000866.4 | 72918 | 73328 | - | NP_049747.1 | 136 | 16034.61 | -6.0 | 4.6254 | hypothetical protein | phrog_17649 ; phrog_33719 ; phrog_4811 ; phrog_1411 | |
NC_000866.4 | 73329 | 73514 | - | NP_049748.1 | 61 | 6557.94 | 1.0 | 7.7990 | hypothetical protein | phrog_1692 | |
NC_000866.4 | 73591 | 73878 | - | NP_049749.1 | 95 | 10176.80 | 3.0 | 9.6274 | internal virion protein | phrog_4363 | PF11634.11 |
NC_000866.4 | 73952 | 74410 | - | NP_049750.1 | 152 | 17244.53 | -4.5 | 4.9749 | RNA ligase | phrog_755 | |
NC_000866.4 | 74407 | 74649 | - | NP_049751.1 | 80 | 8730.81 | -9.0 | 4.0694 | tail fiber chaperone | phrog_1002 | PF17594.5 |
NC_000866.4 | 74649 | 75374 | - | NP_049752.1 | 241 | 27329.15 | -5.5 | 4.8518 | deoxynucleoside monophosphate kinase | phrog_139 | |
NC_000866.4 | 75424 | 75954 | - | NP_049753.1 | 176 | 19712.27 | -9.5 | 4.1283 | tail protein | phrog_45 | PF06841.15 |
NC_000866.4 | 76061 | 76885 | - | NP_049754.1 | 274 | 31610.09 | 31.0 | 10.7851 | DNA end protector | phrog_32288 ; phrog_429 | |
NC_000866.4 | 76885 | 77337 | - | NP_049755.1 | 150 | 17627.41 | 12.5 | 10.3980 | head closure | phrog_14892 ; phrog_218 | PF08722.14 |
Hit | Query start | Query end | Hit start | Hit end | TMscore(ali) | TMscore(avg) |
---|---|---|---|---|---|---|
MGYP001306717441.pdb | 1 | 137 | 8 | 147 | 0.9749 | 0.9089 |
MGYP001124013561.pdb | 1 | 137 | 8 | 144 | 0.9608 | 0.9075 |
MGYP001021327017.pdb | 1 | 137 | 2 | 138 | 0.9445 | 0.9068 |
MGYP002769065333.pdb | 1 | 137 | 9 | 147 | 0.9661 | 0.9034 |
MGYP003610834631.pdb | 1 | 137 | 3 | 141 | 0.926 | 0.8928 |
MGYP003620843858.pdb | 1 | 137 | 8 | 146 | 0.9459 | 0.8824 |
MGYP003608119546.pdb | 1 | 137 | 7 | 148 | 0.9304 | 0.8708 |
MGYP003635017775.pdb | 1 | 137 | 3 | 145 | 0.9189 | 0.8633 |
MGYP001774826977.pdb | 1 | 137 | 11 | 149 | 0.9199 | 0.8566 |
MGYP003526094176.pdb | 1 | 137 | 10 | 157 | 0.9417 | 0.854 |
Fam ID | Seed protein | Member count | Model | Alignment | APIS016 | NP_049750.1 | 41 | HMM model | Member alignment |
---|
Member | pident | evalue | bitscore | qcovs | phage | host | SourceDB | Pfam | Phrog |
---|---|---|---|---|---|---|---|---|---|
HM035025_00145 | 99.342 | 2.76e-108 | 313 | 100% | Shigella phage Shfl2 | Shigella | INPHARED | phrog_755 | |
IMGVR_UViG_3300045988_154884|3300045988|Ga0495776_101933_102131_102586 | 88.079 | 1.30e-94 | 278 | 99% | IMGVR | phrog_755 | |||
IMGVR_UViG_651703089_000001|651703089|651709829 | 99.338 | 2.40e-107 | 310 | 99% | IMGVR | phrog_755 | |||
KX009778_00148 | 99.338 | 7.65e-108 | 311 | 99% | Escherichia phage UFV-AREG1 | Escherichia | INPHARED | phrog_755 | |
MF001359_00146 | 99.342 | 1.06e-108 | 314 | 100% | Escherichia phage EC121 | Escherichia | INPHARED | phrog_755 | |
MF001360_00175 | 100.000 | 8.29e-105 | 304 | 96% | Escherichia phage ECO4 | Escherichia | INPHARED | phrog_755 | |
MGV-GENOME-0373836_158 | 100.000 | 3.25e-109 | 315 | 100% | MGV | phrog_755 | |||
MGV-GENOME-0375647_201 | 88.079 | 1.35e-94 | 278 | 99% | MGV | phrog_755 | |||
MGV-GENOME-0377517_209 | 86.093 | 7.04e-95 | 279 | 99% | MGV | phrog_755 | |||
MGV-GENOME-0377569_108 | 100.000 | 3.29e-108 | 312 | 99% | MGV | phrog_755 | |||
MGV-GENOME-0377573_125 | 86.093 | 1.07e-94 | 278 | 99% | MGV | phrog_755 | |||
MGV-GENOME-0377602_246 | 99.338 | 3.12e-107 | 310 | 99% | MGV | phrog_755 | |||
MGV-GENOME-0377637_9 | 85.430 | 3.46e-94 | 277 | 99% | MGV | phrog_755 | |||
MK327936_00142 | 99.338 | 7.75e-107 | 309 | 99% | Escherichia phage vB_EcoM_G2540 | Escherichia | INPHARED | phrog_755 | |
MK373782_00151 | 84.768 | 3.98e-94 | 277 | 99% | Escherichia phage vB_EcoM_KAW3E185 | Escherichia | INPHARED | phrog_755 | |
MK373786_00155 | 99.338 | 8.73e-108 | 311 | 99% | Escherichia phage vB_EcoM_R5505 | Escherichia | INPHARED | phrog_755 | |
MK524178_00242 | 86.093 | 1.44e-94 | 278 | 99% | Escherichia phage PHB12 | Escherichia | INPHARED | phrog_755 | |
MK962750_00147 | 99.342 | 9.01e-109 | 314 | 100% | Shigella phage CM8 | Shigella | INPHARED | phrog_755 | |
MK962752_00155 | 99.338 | 1.15e-107 | 311 | 99% | Shigella phage JK23 | Shigella | INPHARED | phrog_755 | |
MK962755_00149 | 99.342 | 2.19e-108 | 313 | 100% | Shigella phage JK38 | Shigella | INPHARED | phrog_755 | |
MN648445_00012 | 85.430 | 3.34e-94 | 277 | 99% | Escherichia phage FP43 | Escherichia | INPHARED | phrog_755 | |
MT446387_00104 | 98.675 | 6.50e-107 | 309 | 99% | Escherichia phage TH09 | Escherichia | INPHARED | phrog_755 | |
MT682710_00039 | 98.013 | 6.96e-106 | 306 | 99% | Escherichia phage vB_EcoM_FT | Escherichia | INPHARED | phrog_755 | |
MW341595_00202 | 99.338 | 6.56e-108 | 311 | 99% | Shigella phage Sfk20 | Shigella | INPHARED | phrog_755 | |
MW749001_00151 | 99.338 | 1.03e-107 | 311 | 99% | Escherichia phage vB_EcoM_Kelasse | Escherichia | INPHARED | phrog_755 | |
MZ311865_00060 | 86.093 | 1.03e-94 | 278 | 99% | Escherichia phage vB_EcoM_LNA2 | Escherichia | INPHARED | phrog_755 | |
MZ501047_00254 | 85.430 | 1.01e-94 | 278 | 99% | Escherichia phage AlbertHofmann | Escherichia | INPHARED | phrog_755 | |
MZ501056_00249 | 86.093 | 6.81e-95 | 279 | 99% | Escherichia phage ChristianSchoenbein | Escherichia | INPHARED | phrog_755 | |
MZ502380_00147 | 98.052 | 4.82e-106 | 307 | 99% | Escherichia phage vB_EcoM_Nami | Escherichia | INPHARED | phrog_755 | |
NP_049750.1 | 100.000 | 8.09e-116 | 315 | 100% | T4 of E. coli | Escherichia coli | NCBI | phrog_755 | |
OK040907_00146 | 99.338 | 1.45e-107 | 311 | 99% | Enterobacteria phage Ac3 | Enterobacteria | INPHARED | phrog_755 | |
OL770073_00167 | 99.338 | 5.69e-108 | 312 | 99% | Escherichia phage vB_EcoM-RPN226 | Escherichia | INPHARED | phrog_755 | |
OL770074_00244 | 86.093 | 8.29e-95 | 278 | 99% | Escherichia phage vB_EcoM-RPN187 | Escherichia | INPHARED | phrog_755 | |
OL870317_00149 | 99.342 | 9.73e-109 | 314 | 100% | Escherichia phage UTI-E4 | Escherichia | INPHARED | phrog_755 | |
ON528740_00148 | 99.338 | 1.67e-107 | 311 | 99% | Shigella phage ESh30 | Shigella | INPHARED | phrog_755 | |
OP611477_00195 | 99.338 | 1.09e-107 | 311 | 99% | Escherichia virus CAM-21 | Escherichia | INPHARED | phrog_755 | |
OQ067374_00246 | 85.430 | 3.30e-94 | 277 | 99% | Escherichia phage a20 | Escherichia | INPHARED | phrog_755 | |
OQ466432_00246 | 100.000 | 3.18e-108 | 312 | 99% | Escherichia phage ADUt | Escherichia | INPHARED | phrog_755 | |
OQ703618_00035 | 84.768 | 4.11e-94 | 277 | 99% | Escherichia phage GADS24 | Escherichia | INPHARED | phrog_755 | |
OQ721911_00151 | 99.338 | 4.88e-108 | 312 | 99% | Escherichia phage vB_VIPECOOM03 | Escherichia | INPHARED | phrog_755 | |
uvig_225001_246 | 99.338 | 3.02e-107 | 310 | 99% | GPD | phrog_755 |
APIS | Contig | Range |
---|---|---|
APIS016 | NC_000866.4 | 71253 - 77337 |