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Browse anti-prokaryotic immune system families by CLAN ID

AD families AD genes Defense system CLAN ID Phages/MGEs References Description
APIS023 gp5.9 RecBCD CLAN017 T7 of E. coli PMID:36533901 Gp5.9 completely inhibits RecBCD by preventing it from binding to DNA. The RecBCD-gp5.9 structure shows that gp5.9 acts by substrate mimicry, binding predominantly to the RecB arm domain and competing sterically for the DNA binding site.