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Seed proteins  | Seed genomic context  | Seed protein 3D structures  |  Structural homologs  |  Family infomation  | Homology to other families  | Family members, sources, and their hosts  

Seed protein information help

APIS family ID APIS018
Inhibited defense system restriction-modification (RM)
CLAN ID CLAN017
Seed protein property
Accession ID Gene name Protein length Molecular weight Isoelectric point Charge
NP_049868.1 gene_page: Arn 92 10900.49 4.2444 -7.5
Phage property
Phage Assembly id
T4 of E. coli GCF_000836945.1
PMID/References PMID:25118281
PDB structures 3WX4;
Pfam domains
Phrog phrog_3151
Host taxa d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia;s__Escherichia coli
Gene Location Start: 161312;  End: 161590;  Strand: -
Description T4 phage protein Arn (Anti restriction nuclease) was identified as an inhibitor of the restriction enzyme McrBC.

Seed genomic context      Download table help

Genome accession Start End Strand Protein ID Length Molecular weight Charge Isoelectric point Function Phrog PFAM
NC_000866.4 156542 159622 + NP_049863.1 1026 109224.62 16.0 8.7380 long tail fiber protein distal subunit phrog_35830 ; phrog_2097 ; phrog_25747 ; phrog_1699 ; phrog_24369 ; phrog_33642 ; phrog_6459 ; phrog_20242 ; phrog_6256 ; phrog_1858 ; phrog_10316 ; phrog_14307 ; phrog_19966 ; phrog_20472 ; phrog_295 ; phrog_8239 ; phrog_3100 ; phrog_36248 ; phrog_12846 ; phrog_523 ; phrog_327 ; phrog_2631 ; phrog_26622 ; phrog_32294 ; phrog_35174 ; phrog_19618 ; phrog_6859 ; phrog_13229 ; phrog_29752 PF03335.16 ;PF07484.15 ;PF03335.16 ;PF03335.16 ;PF03335.16 ;PF03335.16 ;PF03335.16 ;PF03335.16
NC_000866.4 159649 160200 + NP_049864.1 183 22310.30 1.0 6.7689 tail fiber assembly phrog_105 ; phrog_15280 ; phrog_7290 ; phrog_1807
NC_000866.4 160221 160877 + NP_049865.1 218 25175.74 3.0 7.8511 holin phrog_34589 ; phrog_860 PF11031.11
NC_000866.4 160878 161150 - NP_049866.1 90 10590.03 -1.5 5.1881 anti-sigma factor phrog_14527 ; phrog_1166 PF09010.13
NC_000866.4 161163 161315 - NP_049867.1 50 5935.44 -5.0 4.3167 hypothetical protein phrog_3762 ; phrog_24016
NC_000866.4 161312 161590 - NP_049868.1 92 10900.49 -7.5 4.2444 inhibitor of MrcBC restriction phrog_3151
NC_000866.4 161674 161805 - NP_049869.1 43 5172.95 3.0 8.2824 hypothetical protein phrog_6212 ; phrog_4452
NC_000866.4 161876 162172 - NP_049870.1 98 11365.34 2.0 8.4659 hypothetical protein phrog_1844 ; phrog_27806
NC_000866.4 162172 162630 - NP_049871.1 152 17836.25 -4.0 4.8930 hypothetical protein phrog_839
NC_000866.4 162627 162833 - NP_049872.2 68 7899.08 3.0 9.9519 hypothetical protein phrog_33982 ; phrog_1594
NC_000866.4 162967 163602 - NP_049873.1 211 23574.32 4.5 9.1923 MotA-like activator of middle period transcription phrog_1345 PF09114.13 ;PF09158.13

Seed genomic context- JBrowse     

PDB structure: 3WX4 ; Download help

Full Sequence      Download help

Structural homologs

No homologs found in AlphaFold database

No homologs found in esmfold database

Family information      Download help

Fam ID Seed protein Member count Model Alignment
APIS018 NP_049868.1 70 HMM model Member alignment

Host Taxa distribution

Length distribution

Homology to other families       help

Clan ID: CLAN017

APIS018 has no similar APIS family.

Family members, sources, and their hosts        help

Results of representative protein blast against members.
Member pident evalue bitscore qcovs phage host SourceDB Pfam Phrog
DQ904452_00249 95.652 8.04e-57 178 100% Escherichia phage RB32 Escherichia INPHARED phrog_3151
IMGVR_UViG_3300006879_000249|3300006879|Ga0079226_100163416 97.826 3.09e-57 179 100% IMGVR phrog_3151
IMGVR_UViG_3300010279_000008|3300010279|Ga0129313_100027143 96.739 5.23e-57 178 100% IMGVR phrog_3151
IMGVR_UViG_3300045988_132814|3300045988|Ga0495776_001669_165061_165339 95.652 3.86e-56 176 100% IMGVR phrog_3151
JX128259_00259 95.652 1.26e-55 175 100% Escherichia phage ECML-134 Escherichia INPHARED phrog_3151
KM607000_00253 94.565 3.54e-56 176 100% Enterobacteria phage RB27 Enterobacteria INPHARED phrog_3151
KX009778_00259 94.565 1.06e-55 175 100% Escherichia phage UFV-AREG1 Escherichia INPHARED phrog_3151
MF001359_00258 95.652 1.47e-55 175 100% Escherichia phage EC121 Escherichia INPHARED phrog_3151
MG781191_00256 96.739 2.66e-56 177 100% Escherichia phage vB_EcoM-fHoEco02 Escherichia INPHARED phrog_3151
MG867727_00258 94.565 5.88e-55 173 100% Escherichia phage vB_EcoM-G28 Escherichia INPHARED phrog_3151
MGV-GENOME-0371733_137 96.739 5.23e-57 178 100% MGV phrog_3151
MGV-GENOME-0377341_131 96.739 4.29e-57 179 100% MGV phrog_3151
MGV-GENOME-0377451_137 95.652 2.60e-56 177 100% MGV phrog_3151
MGV-GENOME-0377569_267 95.652 3.98e-56 176 100% MGV phrog_3151
MGV-GENOME-0377588_138 94.565 1.46e-53 170 100% MGV phrog_3151
MGV-GENOME-0377602_92 94.565 3.95e-55 174 100% MGV phrog_3151
MK327944_00257 96.739 2.44e-56 177 100% Escherichia phage vB_EcoM_G2540-3 Escherichia INPHARED phrog_3151
MK327946_00264 95.652 2.44e-55 174 100% Escherichia phage vB_EcoM_G4507 Escherichia INPHARED phrog_3151
MK373781_00259 96.739 7.47e-56 176 100% Escherichia phage vB_EcoM_KAW1E185 Escherichia INPHARED phrog_3151
MK962752_00263 96.739 5.07e-57 178 100% Shigella phage JK23 Shigella INPHARED phrog_3151
MN781580_00257 96.739 8.97e-57 178 100% Shigella phage KRT47 Shigella INPHARED phrog_3151
MT176425_00258 96.739 3.24e-56 176 100% Citrobacter phage PhiZZ23 Citrobacter INPHARED phrog_3151
MT515756_00090 95.652 2.26e-56 177 100% Yersinia phage PYps55T Yersinia INPHARED phrog_3151
MT682713_00259 95.652 5.55e-56 176 100% Escherichia phage vB_EcoM_Ozark Escherichia INPHARED phrog_3151
MT764206_00089 94.565 3.43e-55 174 100% Escherichia phage JEP6 Escherichia INPHARED phrog_3151
MT884007_00084 96.739 7.44e-57 178 100% Escherichia phage vb_EcoM_bov10K1 Escherichia INPHARED phrog_3151
MT932213_00251 96.739 2.66e-56 177 100% Escherichia phage VEc74 Escherichia INPHARED phrog_3151
MT984581_00254 97.727 6.25e-55 173 96% Escherichia phage T4 Escherichia INPHARED phrog_3151
MW341595_00042 93.478 2.29e-54 172 100% Shigella phage Sfk20 Shigella INPHARED phrog_3151
MW749000_00254 94.565 4.67e-55 173 100% Hafnia phage vB_HpaM_IsaacDaniel Hafnia INPHARED phrog_3151
MW822007_00241 93.478 1.80e-54 172 100% Escherichia phage BF15 Escherichia INPHARED phrog_3151
MZ065353_00136 94.565 5.39e-55 173 100% Escherichia virus KFS-EC3 Escherichia INPHARED phrog_3151
MZ150757_00260 94.565 1.32e-55 175 100% Salmonella phage Lv5cm Salmonella INPHARED phrog_3151
MZ170041_00266 96.739 2.66e-56 177 100% Escherichia phage vB_EcoM_FN Escherichia INPHARED phrog_3151
MZ501096_00090 94.565 2.39e-55 174 100% Escherichia phage Paracelsus Escherichia INPHARED phrog_3151
MZ501098_00087 96.739 2.00e-56 177 100% Escherichia phage PaulHMueller Escherichia INPHARED phrog_3151
MZ501106_00092 95.652 3.07e-56 176 100% Escherichia phage TadeuszReichstein Escherichia INPHARED phrog_3151
MZ726795_00257 95.652 7.72e-56 175 100% Escherichia phage vB_EcoM_ASO78A Escherichia INPHARED phrog_3151
NP_049868.1 100.000 1.78e-65 183 100% T4 of E. coli Escherichia coli NCBI phrog_3151
OK018184_00270 93.478 1.31e-53 170 100% Shigella phage CT01 Shigella INPHARED phrog_3151
OK148441_00116 95.652 2.02e-56 177 100% Escherichia phage MLP2 Escherichia INPHARED phrog_3151
OL615012_00253 95.652 1.11e-55 175 100% Shigella phage vB_SboM_Phaginator Shigella INPHARED phrog_3151
OL656107_00257 95.652 1.96e-55 174 100% Salmonella phage UAB_60 Salmonella INPHARED phrog_3151
OL770073_00009 95.652 2.94e-56 176 100% Escherichia phage vB_EcoM-RPN226 Escherichia INPHARED phrog_3151
OL956808_00262 95.652 2.55e-56 177 100% Escherichia phage vB_EcoM-S1P5QW Escherichia INPHARED phrog_3151
OL960581_00252 94.565 7.17e-55 173 100% Escherichia phage vB_EcoM_SA20RB Escherichia INPHARED phrog_3151
OM135583_00249 94.565 3.83e-55 174 100% Escherichia phage EP01 Escherichia INPHARED phrog_3151
OM339528_00019 96.739 1.50e-56 177 100% Enterobacteria phage SV76 Enterobacteria INPHARED phrog_3151
ON528736_00097 95.652 1.34e-55 175 100% Shigella phage ESh26 Shigella INPHARED phrog_3151
ON528738_00009 95.652 2.52e-56 177 100% Shigella phage ESh28 Shigella INPHARED phrog_3151
ON528739_00180 95.652 6.91e-56 176 100% Shigella phage ESh29 Shigella INPHARED phrog_3151
ON528745_00259 96.739 2.00e-56 177 100% Shigella phage ESH35 Shigella INPHARED phrog_3151
ON528746_00271 94.565 4.09e-55 174 100% Shigella phage ESh36 Shigella INPHARED phrog_3151
ON720975_00212 92.391 1.89e-52 167 100% Salmonella phage GRNsp7 Salmonella INPHARED phrog_3151
OP172785_00164 95.652 2.23e-56 177 100% Escherichia phage ECO07P2 Escherichia INPHARED phrog_3151
OP172786_00268 93.478 4.53e-54 171 100% Escherichia phage ECO07P3 Escherichia INPHARED phrog_3151
OP555982_00257 96.739 1.26e-56 177 100% Escherichia phage vB_EcoM-UFV11 Escherichia INPHARED phrog_3151
OP856590_00253 92.391 1.12e-52 167 100% Escherichia phage Ec_MI-02 Escherichia INPHARED phrog_3151
OP870144_00256 93.478 6.78e-55 173 100% Escherichia phage vB_Eco_F25 Escherichia INPHARED phrog_3151
OQ067375_00090 96.739 5.07e-57 178 100% Escherichia phage a48 Escherichia INPHARED phrog_3151
OQ067376_00087 96.739 1.33e-56 177 100% Escherichia phage a51 Escherichia INPHARED phrog_3151
OQ174500_00268 96.739 2.63e-56 177 100% Escherichia phage REP1 Escherichia INPHARED phrog_3151
OQ174502_00099 96.739 5.07e-57 178 100% Escherichia phage REP3 Escherichia INPHARED phrog_3151
OQ174503_00073 95.652 1.17e-55 175 100% Escherichia phage REP4 Escherichia INPHARED phrog_3151
OQ349392_00021 95.652 5.99e-56 176 100% Escherichia phage KIT06 Escherichia INPHARED phrog_3151
OQ466432_00138 96.739 4.16e-57 179 100% Escherichia phage ADUt Escherichia INPHARED phrog_3151
OQ599309_00260 97.826 2.99e-57 179 100% Escherichia phage 107 Escherichia INPHARED phrog_3151
OQ721911_00259 94.565 1.42e-53 170 100% Escherichia phage vB_VIPECOOM03 Escherichia INPHARED phrog_3151
uvig_249051_55 90.217 1.48e-51 164 100% GPD phrog_3151
uvig_585812_38 96.739 1.57e-56 177 100% GPD phrog_3151
APIS Contig Range
APIS018 NC_000866.4 156542 - 163602

Gene cluster comparison plot by clinker      Download html