| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS148 | OrbA | bacteriophage exclusion (BREX) | CLAN058 | Vibrio phage ICP1 | PMID:34326207 | Clinical phage ICP1 overcomes cocirculating SXT ICEs through acquisition of epigenetic RM as well as an anti-BREX protein, OrbA. |