| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS103 | NTases | CBASS, Pycsar and CRISPR–Cas (type III) | CLAN042 | Bacillus phage BCP1 | PMID:36952342 | A family of bacteriophage nucleotidyltransferases (NTases) that synthesize competitor cyclic dinucleotide (CDN) ligands and inhibit TIR NADase effectors activated via a linked STING CDN sensor domain (TIR-STING). |
| APIS121 | CLAN042 | |||||
| APIS122 | CLAN042 | |||||
| APIS137 | CLAN042 | |||||
| APIS144 | CLAN042 | |||||
| APIS155 | CLAN042 | |||||
| APIS163 | CLAN042 | |||||
| APIS168 | CLAN042 | |||||
| APIS189 | CLAN042 |