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Seed proteins  | Seed genomic context  | Seed protein 3D structures  |  Structural homologs  |  Family infomation  | Homology to other families  | Family members, sources, and their hosts  

Seed protein information help

APIS family ID APIS019
Inhibited defense system O-antigen-based barrier
CLAN ID CLAN018
Seed protein property
Accession ID Gene name Protein length Molecular weight Isoelectric point Charge
NP_050611.1 gene_page: gnarl2 87 9217.64 5.6793 -1.0
Phage property
Phage Assembly id
Escherichia phage Mu GCF_000837225.1
PMID/References Silas et al., 2023
PDB structures ;
Pfam domains
Phrog phrog_10252
Host taxa d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia;
Gene Location Start: 4784;  End: 5047;  Strand: +
Description Putative O-antigen modifiers, interfere with O-antigen biosynthesis.

Seed genomic context      Download table help

Genome accession Start End Strand Protein ID Length Molecular weight Charge Isoelectric point Function Phrog PFAM
NC_000929.1 1099 1326 + NP_050606.1 75 8505.73 5.0 10.1017 transcriptional repressor phrog_769 PF13693.9
NC_000929.1 1328 3319 + NP_050607.1 663 75003.29 15.5 8.9500 Mu transposase C-terminal domain-containing protein phrog_14727 ; phrog_18348 ; phrog_15639 ; phrog_7148 ; phrog_13142 ; phrog_19169 ; phrog_19841 ; phrog_310 PF02316.19 ;PF09039.14 ;PF02914.18 ;PF09299.14
NC_000929.1 3358 4296 + NP_050608.1 312 35106.14 4.5 8.2714 DNA transposition protein phrog_29249 ; phrog_27882 ; phrog_296 PF13401.9 ;PF09077.14
NC_000929.1 4315 4539 + NP_050609.1 74 8416.80 6.0 10.6893 Kil protein for bacterial septation inhibition phrog_2743
NC_000929.1 4542 4772 + NP_050610.1 76 8541.08 5.0 8.2297 hypothetical protein phrog_37054 ; phrog_3786
NC_000929.1 4784 5047 + NP_050611.1 87 9217.64 -1.0 5.6793 hypothetical protein phrog_10252
NC_000929.1 5062 5481 + NP_050612.1 139 16310.67 1.0 7.0398 hypothetical protein phrog_3690
NC_000929.1 5482 5781 + NP_050613.1 99 11593.44 7.0 9.4662 transcriptional regulator, D5-like phrog_323
NC_000929.1 5801 6325 + NP_050614.1 174 19045.92 1.0 7.9713 host nuclease inhibitor phrog_18351 ; phrog_491 PF07352.15
NC_000929.1 6424 6954 + NP_050615.1 176 19576.70 -1.0 5.7579 hypothetical protein phrog_1949 ; phrog_24761
NC_000929.1 6954 7484 + NP_050616.1 176 19894.80 6.5 9.2845 hypothetical protein phrog_8700 ; phrog_2314

Seed genomic context- JBrowse     

Predicted 3D structure by alphafold2 with pTM = 0.62 Download help

pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence
90 < plddt <=100 ;
70 < plddt <= 90 ;
50 < plddt <= 70 ;
0 <= plddt <= 50 ;      Download help

Structural homologs

No homologs found in AlphaFold database

No homologs found in esmfold database

Family information      Download help

Fam ID Seed protein Member count Model Alignment
APIS019 NP_050611.1 28 HMM model Member alignment

Host Taxa distribution

Length distribution

Homology to other families       help

Clan ID: CLAN018

APIS019 has no similar APIS family.

Family members, sources, and their hosts        help

Results of representative protein blast against members.

Member pident evalue bitscore qcovs phage host SourceDB Pfam Phrog
IMGVR_UViG_2189573020_000011|2189573020|PaHGM_00488970 72.414 1.31e-33 119 100% IMGVR phrog_10252
IMGVR_UViG_2526164649_000022|2526164649|2526775352 96.552 5.23e-51 163 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2529293223_000009|2529293223|2531651605 97.701 2.61e-52 166 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2529293223_000018|2529293223|2531654559 94.253 6.91e-42 140 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2529293265_000019|2529293265|2531791364 98.851 4.31e-53 168 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2531839127_000011|2531839127|2532320586 89.655 9.71e-46 149 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2531839129_000022|2531839129|2532335534 87.356 3.10e-36 125 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2531839131_000022|2531839131|2532346891 86.207 1.81e-35 124 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2534681626_000015|2534681626|2534783811 85.057 3.69e-43 143 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2541047851_000005|2541047851|2544797323 97.701 7.49e-52 165 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2579778982_000035|2579778982|2581813427 97.701 6.69e-53 167 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2585427793_000015|2585427793|2586735696 77.778 1.41e-28 106 83% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2778261179_000001|2778261179|2779166182 96.552 2.32e-51 164 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2778261222_000001|2778261222|2779330541 71.264 2.73e-33 118 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2778261544_000009|2778261544|2780526469 70.115 1.94e-32 116 100% Escherichia coli IMGVR phrog_10252
IMGVR_UViG_2802429219_000016|2802429219|2804557220 72.414 1.08e-33 119 100% Escherichia marmotae IMGVR phrog_10252
IMGVR_UViG_2802429245_000015|2802429245|2804674025 71.264 3.11e-33 118 100% Escherichia marmotae IMGVR phrog_10252
IMGVR_UViG_2802429253_000009|2802429253|2804708490 70.115 1.67e-32 116 100% Escherichia marmotae IMGVR phrog_10252
IMGVR_UViG_3300045988_091145|3300045988|Ga0495776_179129_20977_21240 97.701 3.84e-52 166 100% Escherichia IMGVR phrog_10252
IMGVR_UViG_648276647_000020|648276647|648349677 97.701 8.09e-52 165 100% Escherichia coli IMGVR phrog_10252
KP010268_00006 96.552 9.23e-52 165 100% Shigella phage SfMu Shigella INPHARED phrog_10252
M64097_00007 98.851 2.36e-53 169 100% INPHARED phrog_10252
MGV-GENOME-0216279_34 97.701 3.95e-52 166 100% Escherichia MGV phrog_10252
MT591577_00048 88.506 4.79e-38 130 100% Yersinia phage vB_YpM_Tongde Yersinia INPHARED phrog_10252
NP_050611.1 100.000 1.31e-60 171 100% Escherichia phage Mu Escherichia NCBI phrog_10252
uvig_318386_9 96.552 2.15e-51 164 100% GPD phrog_10252
uvig_330734_8 73.563 6.14e-33 117 100% GPD phrog_10252
uvig_333462_36 72.414 5.55e-35 122 100% GPD phrog_10252
APIS Contig Range
APIS019 NC_000929.1 1099 - 7484

Gene cluster comparison plot by clinker      Download html