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Seed proteins  | Seed genomic context  | Seed protein 3D structures  |  Structural homologs  |  Family infomation  | Homology to other families  | Family members, sources, and their hosts  

Seed protein information help

APIS family ID APIS021
Inhibited defense system restriction-modification (RM)
CLAN ID CLAN005
Seed protein property
Accession ID Gene name Protein length Molecular weight Isoelectric point Charge
NP_059639.1 gene_page: SieA 164 18701.3 10.0689 5.5
Phage property
Phage Assembly id
Salmonella phage P22 GCF_000845765.1
PMID/References Silas et al., 2023
PDB structures ;
Pfam domains
Phrog phrog_7745,phrog_10966
Host taxa d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Salmonella;
Gene Location Start: 13336;  End: 13830;  Strand: -
Description Superinfection exclusion.

Seed genomic context      Download table help

Genome accession Start End Strand Protein ID Length Molecular weight Charge Isoelectric point Function Phrog PFAM
NC_002371.2 10069 11484 + NP_059637.1 471 50100.57 3.5 8.9820 released from the phage upon host infection phrog_917 ; phrog_28221 ; phrog_36260 ; phrog_2534 PF16928.8
NC_002371.2 13336 13830 - NP_059639.1 164 18701.33 5.5 10.0689 superinfection exclusion SieA-like phrog_7745 ; phrog_10966
NC_002371.2 14240 14419 - NP_059640.1 59 6410.23 6.0 10.6555 hypothetical protein phrog_3202
NC_002371.2 14519 14770 - NP_059641.1 83 9678.07 1.5 8.5279 partition protein ATPase phrog_2685 ; phrog_7906 ; phrog_228 ; phrog_582 ; phrog_4515 ; phrog_795 ; phrog_3178 ; phrog_1388 ; phrog_1287 PF03869.17 ;PF11423.11
NC_002371.2 14861 15022 + NP_059642.1 53 6227.25 4.0 10.6690 Arc-like repressor phrog_2685 ; phrog_7906 ; phrog_228 ; phrog_795 ; phrog_1388 ; phrog_1287 PF03869.17
NC_002371.2 15091 15993 + NP_059643.1 300 34648.96 5.5 8.2150 Ant phrog_2127 ; phrog_377 ; phrog_22471 ; phrog_25722 ; phrog_4792 ; phrog_524 ; phrog_14366 ; phrog_2812 ; phrog_245 ; phrog_5060 ; phrog_37976 PF10547.12 ;PF10548.12
NC_002371.2 16204 18207 + NP_059644.1 667 71856.87 -8.0 5.2484 tail spike protein phrog_1819 ; phrog_17606 ; phrog_20129 ; phrog_4217 ; phrog_34132 ; phrog_19784 ; phrog_21710 ; phrog_29731 ; phrog_22294 ; phrog_17420 ; phrog_8280 ; phrog_19528 ; phrog_16355 ; phrog_23354 ; phrog_33504 ; phrog_5662 ; phrog_21878 ; phrog_8846 ; phrog_29018 ; phrog_8875 ; phrog_1171 ; phrog_20900 ; phrog_26467 ; phrog_18522 ; phrog_8649 ; phrog_28781 ; phrog_7173 PF09008.13 ;PF09251.13
NC_002371.2 8210 8911 + YP_063715.1 233 24720.46 -4.5 4.9033 tail needle protein phrog_1219
NC_002371.2 8911 9366 + YP_063716.1 151 17348.87 2.0 7.2610 head morphogenesis phrog_651 PF11039.11
NC_002371.2 9369 10058 + YP_063717.1 229 23433.01 2.0 9.0363 DNA ejection phrog_598
NC_002371.2 11484 13313 + YP_063718.1 609 64385.58 9.5 9.7141 head morphogenesis phrog_770 ; phrog_21143 ; phrog_29864 ; phrog_29117

Seed genomic context- JBrowse     

Predicted 3D structure by alphafold2 with pTM = 0.55 Download help

pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence
90 < plddt <=100 ;
70 < plddt <= 90 ;
50 < plddt <= 70 ;
0 <= plddt <= 50 ;      Download help

Structural homologs

No homologs found in AlphaFold database

No homologs found in esmfold database

Family information      Download help

Fam ID Seed protein Member count Model Alignment
APIS021 NP_059639.1 32 HMM model Member alignment

Host Taxa distribution

Length distribution

Homology to other families       download full data without filtering help

Clan ID: CLAN005

Hit APIS family E-Value Query Start Query End Hit Start Hit End Immune system Seed protein
APIS042 1.67E-25 7 161 50 206 ivig_4422_51

Family members, sources, and their hosts        help

Results of representative protein blast against members.

Member pident evalue bitscore qcovs phage host SourceDB Pfam Phrog
AF527608_00013 99.390 4.28e-112 323 100% Salmonella phage P22-pbi Salmonella INPHARED phrog_7745 phrog_10966
IMGVR_UViG_2565956772_000009|2565956772|2567029348 100.000 3.36e-109 316 98% Salmonella enterica IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2636415673_000001|2636415673|2637519069 91.463 6.58e-105 305 100% Escherichia coli IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2667527530_000006|2667527530|2668489249 99.390 7.34e-112 323 100% Salmonella enterica IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2711768061_000003|2711768061|2712071463 92.683 1.56e-106 309 100% Escherichia coli IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2734482779_000006|2734482779|2737357242 92.073 2.15e-105 307 100% Escherichia coli IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2778261252_000010|2778261252|2779453028 92.073 2.56e-105 307 100% Escherichia coli IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2778261630_000006|2778261630|2780794877 90.854 4.73e-104 304 100% Escherichia coli IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2778261667_000009|2778261667|2780941467 91.463 4.48e-105 305 100% Escherichia marmotae IMGVR phrog_7745 phrog_10966
IMGVR_UViG_2778261687_000002|2778261687|2781016090 91.463 4.84e-105 305 100% Escherichia coli IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300014597_000051|3300014597|Ga0169859_10001319 91.250 2.65e-101 296 98% Escherichia IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300029076_000063|3300029076|Ga0169233_10018141 91.463 4.68e-105 306 100% Salmonella IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300029253_000364|3300029253|Ga0168699_100080110 92.073 2.29e-105 306 100% Salmonella IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300029653_000163|3300029653|Ga0245224_10008261 90.854 5.90e-104 303 100% Salmonella IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300039384_000090|3300039384|Ga0169689_00046_37075_37557 91.250 2.56e-101 296 98% Salmonella IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300045146_000636|3300045146|Ga0438316_0000512_25126_25620 58.896 4.13e-68 212 99% Serratia IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300045988_085028|3300045988|Ga0495776_161387_6392_6958 90.854 3.63e-104 304 100% Escherichia IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300045988_095810|3300045988|Ga0495776_156641_22855_23337 92.500 3.71e-102 298 98% Enterobacteriaceae IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300045988_104222|3300045988|Ga0495776_161335_4665_5147 92.500 1.07e-102 299 98% Enterobacteriaceae IMGVR phrog_7745 phrog_10966
IMGVR_UViG_3300045988_115574|3300045988|Ga0495776_068481_15670_16236 90.854 1.61e-104 305 100% Escherichia IMGVR phrog_7745 phrog_10966
KR296687_00006 100.000 8.62e-92 271 84% Salmonella phage 25 Salmonella INPHARED phrog_7745 phrog_10966
MGV-GENOME-0167741_5 92.683 4.84e-106 308 100% Escherichia MGV phrog_7745 phrog_10966
MGV-GENOME-0169418_9 90.854 2.65e-104 305 100% Escherichia MGV phrog_7745 phrog_10966
MGV-GENOME-0189529_5 90.854 1.39e-104 305 100% Escherichia MGV phrog_7745 phrog_10966
MGV-GENOME-0203487_32 92.683 1.81e-105 306 100% Escherichia MGV phrog_7745 phrog_10966
MGV-GENOME-0216767_34 91.463 1.37e-104 304 100% Escherichia MGV phrog_7745 phrog_10966
NP_059639.1 100.000 3.09e-119 325 100% Salmonella phage P22 Salmonella NCBI phrog_7745 phrog_10966
uvig_123106_54 91.463 1.33e-104 304 100% GPD phrog_7745 phrog_10966
uvig_124013_16 91.463 3.88e-105 306 100% GPD phrog_7745 phrog_10966
uvig_296832_4 90.854 1.34e-104 305 100% GPD phrog_7745 phrog_10966
uvig_394242_21 92.683 1.74e-105 306 100% GPD phrog_7745 phrog_10966
uvig_67729_8 92.683 4.68e-106 308 100% GPD phrog_7745 phrog_10966
APIS Contig Range
APIS021 NC_002371.2 10069 - 13313

Gene cluster comparison plot by clinker      Download html