| APIS family ID | APIS170 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Inhibited defense system | NAD+ reconstitution pathway (NARP) | |||||||||||||
| CLAN ID | CLAN049 | |||||||||||||
| Seed protein property |
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| Phage property |
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| PMID/References | Osterman et al., 2024 | |||||||||||||
| PDB structures | ; | |||||||||||||
| Pfam domains | PF00293.33,PF01467.31,PF00293.33,PF01467.31 | |||||||||||||
| Phrog | phrog_395,phrog_395 | |||||||||||||
| Host taxa | d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Vibrionales;f__Vibrionaceae;g__Vibrio; | |||||||||||||
| Gene Location | Start: 94507; End: 95532; Strand: + | |||||||||||||
| Description | Nicotinamide mononucleotide adenylyltransferase (Nmnat), capable of generating NAD+ by conjugating AMP to NMN. | |||||||||||||
| Genome accession | Start | End | Strand | Protein ID | Length | Molecular weight | Charge | Isoelectric point | Function | Phrog | PFAM |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NC_005083.2 | 92044 | 92373 | + | NP_899403.1 | 109 | 12480.32 | -0.5 | 6.2081 | hypothetical protein | phrog_13938 | |
| NC_005083.2 | 92370 | 92549 | + | NP_899404.1 | 59 | 6642.51 | -1.0 | 4.9006 | hypothetical protein | phrog_13656 | |
| NC_005083.2 | 92617 | 93378 | + | NP_899405.1 | 253 | 27762.78 | 3.0 | 7.1499 | hypothetical protein | phrog_13584 | |
| NC_005083.2 | 93442 | 93909 | + | NP_899406.1 | 155 | 17502.86 | -1.0 | 6.2832 | hypothetical protein | phrog_14139 ; phrog_27197 | |
| NC_005083.2 | 93890 | 94432 | + | NP_899407.1 | 180 | 20622.35 | -10.0 | 4.4314 | hypothetical protein | phrog_1818 ; phrog_38681 | PF18143.6 |
| NC_005083.2 | 94507 | 95532 | + | NP_899408.1 | 341 | 39396.07 | 5.5 | 7.2039 | cytidyltransferase | phrog_395 ; phrog_395 | PF00293.33 ;PF01467.31 ;PF00293.33 ;PF01467.31 |
| NC_005083.2 | 95555 | 95842 | + | NP_899409.1 | 95 | 10882.34 | 5.0 | 10.3876 | hypothetical protein | phrog_14574 | |
| NC_005083.2 | 95839 | 96465 | + | NP_899410.1 | 208 | 24338.33 | -18.0 | 4.2305 | hypothetical protein | phrog_13623 | |
| NC_005083.2 | 96450 | 96647 | + | NP_899411.1 | 65 | 7681.95 | -1.0 | 5.6939 | hypothetical protein | phrog_14480 | |
| NC_005083.2 | 96644 | 96853 | + | NP_899412.1 | 69 | 8124.93 | -9.5 | 3.8069 | hypothetical protein | phrog_14580 | |
| NC_005083.2 | 96838 | 97056 | + | NP_899413.1 | 72 | 8644.54 | -12.0 | 3.7510 | hypothetical protein | phrog_11499 |
pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.
pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .
| Hit | Query start | Query end | Hit start | Hit end | TMscore(ali) | TMscore(avg) |
|---|---|---|---|---|---|---|
| MGYP003365040244.pdb | 1 | 341 | 3 | 349 | 0.9425 | 0.9239 |
| MGYP002677154047.pdb | 1 | 341 | 3 | 351 | 0.945 | 0.9239 |
| MGYP001363486701.pdb | 1 | 339 | 1 | 339 | 0.9291 | 0.9187 |
| MGYP001111241452.pdb | 1 | 341 | 3 | 343 | 0.9294 | 0.9181 |
| MGYP003387177867.pdb | 1 | 341 | 6 | 343 | 0.9275 | 0.914 |
| MGYP001592028481.pdb | 1 | 341 | 5 | 341 | 0.9216 | 0.9137 |
| MGYP003333461766.pdb | 1 | 341 | 5 | 348 | 0.9305 | 0.9133 |
| MGYP000601395347.pdb | 1 | 341 | 3 | 339 | 0.9219 | 0.9122 |
| MGYP001627277999.pdb | 1 | 341 | 4 | 344 | 0.9256 | 0.9117 |
| MGYP003652350255.pdb | 1 | 341 | 4 | 342 | 0.9198 | 0.9114 |
| Fam ID | Seed protein | Member count | Model | Alignment | APIS170 | NP_899408.1 | 17 | HMM model | Member alignment |
|---|
| Member | pident | evalue | bitscore | qcovs | phage | host | SourceDB | Pfam | Phrog |
|---|---|---|---|---|---|---|---|---|---|
| OQ722176_00276 | 72.600 | 1.126E-160 | 501 | 1.000% | Vibrio phage vB_VspM_VS2 | Vibrio | INPHARED | PF00293 PF01467 | phrog_ |
| OK905446_00344 | 72.600 | 8.216E-161 | 501 | 1.000% | Vibrio phage VS1 | Vibrio | INPHARED | PF00293 PF01467 | phrog_ |
| HQ317393_00020 | 76.400 | 1.954E-172 | 535 | 1.000% | Vibrio phage nt-1 | Vibrio | INPHARED | PF00293 PF01467 | phrog_1198 |
| MG592456_00170 | 71.900 | 2.948E-157 | 491 | 0.991% | Vibrio phage 1.081.O._10N.286.52.C2 | Vibrio | INPHARED | PF00293 PF01467 | phrog_1198 |
| MK568540_00382 | 94.000 | 9.883E-221 | 674 | 1.000% | Vibrio phage Va3 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| KT919973_00030 | 94.100 | 5.262E-221 | 675 | 1.000% | Vibrio phage phi-ST2 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| KT919972_00304 | 94.000 | 9.883E-221 | 674 | 1.000% | Vibrio phage phi-Grn1 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| MT135026_00014 | 98.600 | 9.838E-234 | 711 | 1.000% | Vibrio phage V09 | Vibrio | INPHARED | PF00293 PF01467 | phrog_1198 phrog_395 |
| MW824377_00016 | 69.000 | 1.472E-150 | 471 | 1.000% | Vibrio phage 6E35.1a | Vibrio | INPHARED | PF00293 PF01467 | phrog_1198 |
| MT135025_00201 | 98.600 | 9.838E-234 | 711 | 1.000% | Vibrio phage V07 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| MT612988_00014 | 91.600 | 3.662E-214 | 655 | 1.000% | Vibrio phage vB_ValM_R10Z | Vibrio | INPHARED | PF00293 PF01467 | phrog_ |
| JN849462_00157 | 98.800 | 2.789E-234 | 713 | 1.000% | Vibriophage phi-pp2 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| NP_899408.1 | 100.000 | 6.353E-236 | 718 | 1.000% | Vibrio phage KVP40 | Vibrio | NCBI | PF00293 PF01467 PF00293 PF01467 | phrog_395 phrog_395 |
| ON000910_00260 | 94.300 | 1.089E-221 | 677 | 1.000% | Vibrio phage XZ1 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| MN794232_00160 | 98.400 | 2.532E-233 | 710 | 1.000% | Vibrio phage VH1_2019 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| ON190025_00396 | 94.000 | 7.212E-221 | 674 | 1.000% | Vibrio phage PVA23 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |
| KP671755_00099 | 94.100 | 3.840E-221 | 675 | 1.000% | Vibrio phage ValKK3 | Vibrio | INPHARED | PF00293 PF01467 | phrog_395 |