| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS115 | CLAN049 | |||||
| APIS141 | CLAN049 | |||||
| APIS151 | CLAN049 | |||||
| APIS158 | CLAN049 | |||||
| APIS170 | narp2_nmnat | NAD+ reconstitution pathway (NARP) | CLAN049 | Vibrio phage KVP40 | Osterman et al., 2024 | Nicotinamide mononucleotide adenylyltransferase (Nmnat), capable of generating NAD+ by conjugating AMP to NMN. |