AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
---|---|---|---|---|---|---|
APIS011 | gp4.5 | toxin-antitoxin (TA) | CLAN010 | T7 of E. coli | PMID:23478446 | Protein gp4.5 allows T7 to block Lon (protease) from degrading antitoxins (the SanTA system in E. coli), including SanaA, thereby preventing liberation of SanaT. However, beyond a possible interaction between gp4.5 and Lon in uninfected cells, this speculative model remains untested. |
APIS078 | CLAN010 | Morganella phage vB_MmoP_MP2 | ||||
APIS080 | CLAN010 | Klebsiella phage VLCpiA3d | ||||
APIS084 | CLAN010 | Pectobacterium phage phiPccP-1 |