| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS004 | Acb2 | cyclic oligonucleotide-based antiphage signaling system (CBASS) | CLAN018 | PaMx33 of Pseudomonas aeruginosa | PMID:36750095 | Anti-CBASS protein ("Acb2") that forms a hexamer with three 3',3'-cGAMP molecules and reduces phospholipase activity. |
| APIS055 | CLAN003 | Pseudomonas phage Churro | ||||
| APIS079 | CLAN031 | Pseudomonas phage Skulduggery |