| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS003 | ArdA | restriction-modification (RM) | CLAN003 | plasmid pKM101 of E. coli | PMID:2989658 | DNA mimetics, i.e. structurally and electrostatically imitate the B-form of DNA and thus function as competitive inhibitors of restriction enzymes. |
| APIS051 | CLAN003 | |||||
| APIS063 | CLAN003 | |||||
| APIS067 | CLAN003 | |||||
| APIS072 | CLAN003 | |||||
| APIS097 | CLAN003 | |||||
| APIS098 | CLAN003 | |||||
| APIS128 | CLAN003 | |||||
| APIS146 | CLAN003 | |||||
| APIS147 | CLAN003 | |||||
| APIS159 | CLAN003 | |||||
| APIS176 | CLAN003 | |||||
| APIS187 | CLAN003 | |||||
| APIS194 | CLAN003 | |||||
| ardu | ardu | restriction-modification (RM) | CLAN003 | Shuttle vector pI3 | PMID:10966401 | The gene was from contructed E. coli-D. radiodurans shuttle vector,pI3, and trikingly similar to the known plasmid-encoded antirestriction proteins like ArdA. |