| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS031 | DarA | restriction-modification (RM) | CLAN006 | P1 of E. coli | PMID:3029954 | Bind to phage DNA, thereby masking type I R–M recognition sites and preventing degradation of phage DNA. |
| APIS081 | CLAN006 |