| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS007 | KlcA | restriction-modification (RM) | CLAN003 | IncP-1b plasmid of Bordetella pertussis | PMID:20007596 | ArdB and KlcA act as anti-restriction proteins and inhibit the four main families of Type I RM systems in vivo. |
| APIS038 | CLAN003 | |||||
| APIS048 | CLAN018 | Ralstonia phage YO108_2 |