| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G05570.2 |
| Family | GT48 |
| Protein Properties | Length: 1910 Molecular Weight: 221027 Isoelectric Point: 9.2267 |
| Chromosome | Chromosome/Scaffold: 1 Start: 1647706 End: 1659437 |
| Description | 1,3-beta-glucan synthase component domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT48 | 1007 | 1760 | 0 |
| VPSNLEARRRLTFFSNSLFMDMPPAPKIRNMLSFSVLTPYFSEDVLFSIFGLEQQNEDGVSILFYLQKIFPDEWTNFLERVKCGNEEELRAREDLEEELR LWASYRGQTLTKTVRGMMYYRKALELQAFLDMAKDEELLKGYKALELTSEEASKSGGSLWAQCQALADMKFTFVVSCQQYSIHKRSGDQRAKDILRLMTT YPSIRVAYIDEVEQTHKESYKGTEEKIYYSALVKAAPQTKPMDSSESVQTLDQLIYRIKLPGPAILGEGKPENQNHAIIFTRGEGLQTIDMNQDNYMEEA FKMRNLLQEFLEKHGGVRCPTILGLREHIFTGSVSSLAWFMSNQENSFVTIGQRVLASPLKVRFHYGHPDIFDRLFHLTRGGICKASKVINLSEDIFAGF NSTLREGNVTHHEYIQVGKGRDVGLNQISMFEAKIANGNGEQTLSRDLYRLGHRFDFFRMLSCYFTTIGFYFSTMLTVLTVYVFLYGRLYLVLSGLEEGL SSQRAFRNNKPLEAALASQSFVQIGFLMALPMMMEIGLERGFHNALIEFVLMQLQLASVFFTFQLGTKTHYYGRTLFHGGAEYRGTGRGFVVFHAKFAEN YRFYSRSHFVKGIELMILLLVYQIFGQSYRGVVTYILITVSIWFMVVTWLFAPFLFNPSGFEWQKIVDDWTDWNKWIYNRGGIGVPPEKSWESWWEKELE HLRHSGVRGITLEIFLALRFFIFQYGLVYHLSTFKGKNQSFWVYGASWFVILFI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1910 Download |
| MAQRREPDPP PPQRRILRTQ TVGSLGEAML DSEVVPSSLV EIAPILRVAN EVEASNPRVA 60 YLCRFYAFEK AHRLDPTSSG RGVRQFKTAL LQRLERENET TLAGRQKSDA REMQSFYQHY 120 YKKYIQALLN AADKADRAQL TKAYQTAAVL FEVLKAVNQT EDVEVADEIL ETHNKVEEKT 180 QIYVPYNILP LDPDSQNQAI MRLPEIQAAV AALRNTRGLP WTAGHKKKLD EDILDWLQSM 240 FGFQKDNVLN QREHLILLLA NVHIRQFPKP DQQPKLDDRA LTIVMKKLFR NYKKWCKYLG 300 RKSSLWLPTI QQEVQQRKLL YMGLYLLIWG EAANLRFMPE CLCYIYHHMA FELYGMLAGS 360 VSPMTGEHVK PAYGGEDEAF LQKVVTPIYQ TISKEAKRSR GGKSKHSVWR NYDDLNEYFW 420 SIRCFRLGWP MRADADFFCQ TAEELRLERS EIKSNSGDRW MGKVNFVEIR SFWHIFRSFD 480 RLWSFYILCL QAMIVIAWNG SGELSAIFQG DVFLKVLSVF ITAAILKLAQ AVLDIALSWK 540 ARHSMSLYVK LRYVMKVGAA AVWVVVMAVT YAYSWKNASG FSQTIKNWSD YKIMMLMMWW 600 SQPRLYIGRG MHESALSLFK YTMFWIVLLI SKLAFSYYAE IKPLVGPTKD IMRIHISVYS 660 WHEFFPHAKN NLGVVIALWS PVILVYFMDT QIWYAIVSTL VGGLNGAFRR LGEIRTLGML 720 RSRFQSIPGA FNDCLVPQDN SDDTKKKRFR ATFSRKFDQL PSSKDKEAAR FAQMWNKIIS 780 SFREEDLISD REMELLLVPY WSDPDLDLIR WPPFLLASKI PIALDMAKDS NGKDRELKKR 840 LAVDSYMTCA VRECYASFKN LINYLVVGER EGQVINDIFS KIDEHIEKET LITELNLSAL 900 PDLYGQFVRL IEYLLENREE DKDQIVIVLL NMLELVTRDI MEEEVPSLLE TAHNGSYVKY 960 DVMTPLHQQR KYFSQLRFPV YSQTEAWKEK IKRLHLLLTV KESAMDVPSN LEARRRLTFF 1020 SNSLFMDMPP APKIRNMLSF SVLTPYFSED VLFSIFGLEQ QNEDGVSILF YLQKIFPDEW 1080 TNFLERVKCG NEEELRARED LEEELRLWAS YRGQTLTKTV RGMMYYRKAL ELQAFLDMAK 1140 DEELLKGYKA LELTSEEASK SGGSLWAQCQ ALADMKFTFV VSCQQYSIHK RSGDQRAKDI 1200 LRLMTTYPSI RVAYIDEVEQ THKESYKGTE EKIYYSALVK AAPQTKPMDS SESVQTLDQL 1260 IYRIKLPGPA ILGEGKPENQ NHAIIFTRGE GLQTIDMNQD NYMEEAFKMR NLLQEFLEKH 1320 GGVRCPTILG LREHIFTGSV SSLAWFMSNQ ENSFVTIGQR VLASPLKVRF HYGHPDIFDR 1380 LFHLTRGGIC KASKVINLSE DIFAGFNSTL REGNVTHHEY IQVGKGRDVG LNQISMFEAK 1440 IANGNGEQTL SRDLYRLGHR FDFFRMLSCY FTTIGFYFST MLTVLTVYVF LYGRLYLVLS 1500 GLEEGLSSQR AFRNNKPLEA ALASQSFVQI GFLMALPMMM EIGLERGFHN ALIEFVLMQL 1560 QLASVFFTFQ LGTKTHYYGR TLFHGGAEYR GTGRGFVVFH AKFAENYRFY SRSHFVKGIE 1620 LMILLLVYQI FGQSYRGVVT YILITVSIWF MVVTWLFAPF LFNPSGFEWQ KIVDDWTDWN 1680 KWIYNRGGIG VPPEKSWESW WEKELEHLRH SGVRGITLEI FLALRFFIFQ YGLVYHLSTF 1740 KGKNQSFWVY GASWFVILFI LLIVKGLGVG RRRFSTNFQL LFRIIKGLVF LTFVAILITF 1800 LALPLITIKD LFICMLAFMP TGWGMLLIAQ ACKPLIQQLG IWSSVRTLAR GYEIVMGLLL 1860 FTPVAFLAWF PFVSEFQTRM LFNQAFSRGL QISRILGGQR KDRSSKNKE* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01757 | Acyl_transf_3 | 0.001 | 1713 | 1887 | 176 | + Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long. | ||
| pfam04652 | DUF605 | 7.0e-13 | 42 | 155 | 122 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 3.0e-55 | 316 | 432 | 118 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1007 | 1769 | 826 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0005886 | plasma membrane |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0009504 | cell plate |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD30609.1 | 0 | 1 | 1909 | 1 | 1878 | AC007153_1 Highly similar to putative callose synthase catalytic subunit [Arabidopsis thaliana] |
| GenBank | AAK37413.1 | 0 | 1 | 1909 | 1 | 1950 | AF237733_1 callose synthase 1 catalytic subunit [Arabidopsis thaliana] |
| RefSeq | NP_563743.2 | 0 | 1 | 1909 | 1 | 1950 | CALS1 (CALLOSE SYNTHASE 1); 1,3-beta-glucan synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_850178.1 | 0 | 1 | 1909 | 1 | 1959 | ATGSL03 (GLUCAN SYNTHASE-LIKE 3); 1,3-beta-glucan synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| Swiss-Prot | Q9SL03 | 0 | 1 | 1909 | 1 | 1951 | CALS2_ARATH RecName: Full=Callose synthase 2; AltName: Full=1,3-beta-glucan synthase; AltName: Full=Protein GLUCAN SYNTHASE-LIKE 3 |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2lxm_A | 0.007 | 46 | 165 | 21 | 139 | B Chain B, Lip5-chmp5 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| callose biosynthesis | 13-BETA-GLUCAN-SYNTHASE-RXN | EC-2.4.1.34 | 1,3-β-glucan synthase |
