| APIS107 |
dam |
restriction-modification (RM) |
CLAN045 |
Escherichia phage T4 |
PMID:6307815 |
DNA adenine methylases methylate adenine residues in specific sequences, the methylation site of the host Escherichia coli dam+ methylase. Methylation protects the site against cleavage by the MboI restriction nuclease. |
| APIS136 |
hia5 |
restriction-modification (RM) |
CLAN045 |
Haemophilus influenzae |
PMID:22102579 |
hin1523, nma1821 and hia5 are all DNA adenine N6-methyltransferases. Plasmid DNA overexpressing these novel DNA methyltransferases was resistant to cleavage by many restriction enzymes sensitive to adenine methylation. |
| APIS136 |
hin1523 |
restriction-modification (RM) |
CLAN045 |
Haemophilus influenzae Rd KW20 |
PMID:22102579 |
hin1523, nma1821 and hia5 are all DNA adenine N6-methyltransferases. Plasmid DNA overexpressing these novel DNA methyltransferases was resistant to cleavage by many restriction enzymes sensitive to adenine methylation. |
| APIS136 |
nma1821 |
restriction-modification (RM) |
CLAN045 |
Neisseria meningitidis |
PMID:22102579 |
hin1523, nma1821 and hia5 are all DNA adenine N6-methyltransferases. Plasmid DNA overexpressing these novel DNA methyltransferases was resistant to cleavage by many restriction enzymes sensitive to adenine methylation. |
| APIS152 |
dmt |
restriction-modification (RM) |
CLAN045 |
Escherichia phage P1 |
PMID:14715260 |
DNA methyltransferase (M.EcoP1I) encoded by prophage P1, may protect the phage genome from restriction by type III restriction enzymes and thus could be considered as an anti-restriction system. |
| APIS161 |
|
|
CLAN045 |
|
|
|
| APIS192 |
|
|
CLAN045 |
|
|
|
