Browse dbCAN-PUL Entries

PULID Characterization Method(s) Substrate Organism Publication Publish Date Type Num Genes Num CAZymes CazyFamily
PUL0009 enzyme activity assay, immunoblotting, ATPase assay glycosaminoglycan Streptobacillus moniliformis 28432302
A bacterial ABC transporter enables import of mammalian host glycosaminoglycans. Sci Rep. 2017 Apr 21;7(1):1069. doi: 10.1038/s41598-017-00917-y.
2017 Apr 21 degradation 15 4 PL8, PL8, GH88
PUL0018 rapid plate method growth assay, gene deletion mutant and growth assay, RT-PCR, enzyme activity assay glycosaminoglycan Streptococcus pneumoniae 22311922
Streptococcus pneumoniae can utilize multiple sources of hyaluronic acid for growth. Infect Immun. 2012 Apr;80(4):1390-8. doi: 10.1128/IAI.05756-11. Epub 2012 Feb 6.
2012 Apr degradation 12 3 CBM70, PL8_1, PL8, GH88, PL12_1
PUL0020 rapid plate method growth assay, adhesion assay glycosaminoglycan Lactobacillus rhamnosus 30006634
Probiotics in human gut microbiota can degrade host glycosaminoglycans. Sci Rep. 2018 Jul 13;8(1):10674. doi: 10.1038/s41598-018-28886-w.
2018 Jul 13 degradation 16 3 PL12_1, PL12, GH88, PL8
PUL0145 enzyme activity assay glycosaminoglycan, chondroitin sulfate Bacteroides thetaiotaomicron 30262663
The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29. J Biol Chem. 2018 Nov 16;293(46):17906-17916. doi: 10.1074/jbc.RA118.004510. Epub 2018 Sep 27.
2018 Nov 16 degradation 27 5 PL8, PL8_2, PL29, GH2, GH88, PL8_2
PUL0210 enzyme activity assay N-glycan Clostridium perfringens 25605731
Metabolic fate of unsaturated glucuronic/iduronic acids from glycosaminoglycans: molecular identification and structure determination of streptococcal isomerase and dehydrogenase. J Biol Chem. 2015 Mar 6;290(10):6281-92. doi: 10.1074/jbc.M114.604546. Epub 2015 Jan 20.
2015 Mar 6 degradation 13 3 PL8, GH88, PL12_1
PUL0377 microarray, qPCR glycosaminoglycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 27 3 PL8_2, PL8, PL29, GH2, GH88, PL8_2