| PULID | Characterization Method(s) | Substrate | Organism | Publication | Publish Date | Type | Num Genes | Num CAZymes | CazyFamily |
|---|---|---|---|---|---|---|---|---|---|
| PUL0009 | enzyme activity assay, immunoblotting, ATPase assay | glycosaminoglycan | Streptobacillus moniliformis | 28432302 A bacterial ABC transporter enables import of mammalian host glycosaminoglycans. Sci Rep. 2017 Apr 21;7(1):1069. doi: 10.1038/s41598-017-00917-y. |
2017 Apr 21 | degradation | 15 | 4 | PL8, PL8, GH88 |
| PUL0018 | rapid plate method growth assay, gene deletion mutant and growth assay, RT-PCR, enzyme activity assay | glycosaminoglycan | Streptococcus pneumoniae | 22311922 Streptococcus pneumoniae can utilize multiple sources of hyaluronic acid for growth. Infect Immun. 2012 Apr;80(4):1390-8. doi: 10.1128/IAI.05756-11. Epub 2012 Feb 6. |
2012 Apr | degradation | 12 | 3 | CBM70, PL8_1, PL8, GH88, PL12_1 |
| PUL0020 | rapid plate method growth assay, adhesion assay | glycosaminoglycan | Lactobacillus rhamnosus | 30006634 Probiotics in human gut microbiota can degrade host glycosaminoglycans. Sci Rep. 2018 Jul 13;8(1):10674. doi: 10.1038/s41598-018-28886-w. |
2018 Jul 13 | degradation | 16 | 3 | PL12_1, PL12, GH88, PL8 |
| PUL0145 | enzyme activity assay | glycosaminoglycan, chondroitin sulfate | Bacteroides thetaiotaomicron | 30262663 The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29. J Biol Chem. 2018 Nov 16;293(46):17906-17916. doi: 10.1074/jbc.RA118.004510. Epub 2018 Sep 27. |
2018 Nov 16 | degradation | 27 | 5 | PL8, PL8_2, PL29, GH2, GH88, PL8_2 |
| PUL0210 | enzyme activity assay | N-glycan | Clostridium perfringens | 25605731 Metabolic fate of unsaturated glucuronic/iduronic acids from glycosaminoglycans: molecular identification and structure determination of streptococcal isomerase and dehydrogenase. J Biol Chem. 2015 Mar 6;290(10):6281-92. doi: 10.1074/jbc.M114.604546. Epub 2015 Jan 20. |
2015 Mar 6 | degradation | 13 | 3 | PL8, GH88, PL12_1 |
| PUL0377 | microarray, qPCR | glycosaminoglycan | Bacteroides thetaiotaomicron | 18996345 Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. |
2008 Nov 13 | degradation | 27 | 3 | PL8_2, PL8, PL29, GH2, GH88, PL8_2 |
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