Browse dbCAN-PUL Entries

PULID Characterization Method(s) Substrate Organism Publication Publish Date Type Num Genes Num CAZymes CazyFamily
PUL0091 sequence homology analysis O-glycan, N-glycan Bacteroides vulgatus 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 8 6 CE9, GH2, GH92, GH20, GH20, GH2
PUL0092 sequence homology analysis O-glycan, N-glycan Bacteroides vulgatus 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 10 4 GH20, GH2, GH20, GH33
PUL0093 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 24 7 CE9, GH2, GH92, GH20, GH20, GH2
PUL0094 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 25 5 GH27, GH33, GH20, GH2, GH20
PUL0095 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 17 5 GH27, GH33, GH20, GH2, GH20
PUL0096 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 22 10 GH33, GH20, GH2, GH20, GH20, GH92, GH2, CE9, GH29, GH97
PUL0097 sequence homology analysis O-glycan, N-glycan Bacteroides massiliensis 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 15 10 GH33, GH20, GH2, GH20, GH20, GH92, GH2, CE9
PUL0098 sequence homology analysis O-glycan, N-glycan Bacteroides plebeius 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 12 3 GH33
PUL0101 sequence homology analysis O-glycan, N-glycan Bacteroides plebeius 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 19 5 CBM67, GH78, GH3, GH115, GH97
PUL0102 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 25 4 GH20, GH29, GH33, CBM67, GH78
PUL0103 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 31 2 CBM67, GH78, GH33
PUL0104 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 33 3 GH33, CBM67, GH78
PUL0105 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 36 5 GH33, CBM67, GH78, GH3, GH115, GH97
PUL0106 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 22 4 GH20, GH2, GH2, GH2
PUL0107 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 27 4 GH1
PUL0108 sequence homology analysis O-glycan, N-glycan Bacteroides uniformis 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 27 3 GH2, GH3
PUL0109 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 28 3 GH2
PUL0110 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 28 3 GH2
PUL0112 fosmid library screen, lectin binding assay O-glycan, N-glycan uncultured bacterium 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 25 1 GH20, GH2, GH2, GH2
PUL0113 sequence homology analysis O-glycan, N-glycan Faecalibacterium prausnitzii 31275257
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 23 1 GH1
PUL0115 expression of recombinant proteins, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 7 7 GH33, GH20, GH2, GH20, GH20, GH2
PUL0116 expression of recombinant proteins, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 2 1 GH20
PUL0117 expression of recombinant proteins, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 22 4 GH92, GH130, GH163, GH20
PUL0119 expression of recombinant proteins, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 2 1 CBM32, GH29
PUL0120 expression of recombinant proteins, RNA-Seq, differential gene expression N-glycan, mucin Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 6 2 CBM14, GH18
PUL0171 qRT-PCR, RNA-Seq N-glycan Bacteroides fragilis 27353652
cis-Encoded Small RNAs, a Conserved Mechanism for Repression of Polysaccharide Utilization in Bacteroides. J Bacteriol. 2016 Aug 25;198(18):2410-8. doi: 10.1128/JB.00381-16. Print 2016 Sep 15.
2016 Sep 15 degradation 7 1 GH18
PUL0194 enzyme activity assay, gene deletion mutant and growth assay N-glycan Streptococcus pneumoniae 28056108
Molecular Characterization of N-glycan Degradation and Transport in Streptococcus pneumoniae and Its Contribution to Virulence. PLoS Pathog. 2017 Jan 5;13(1):e1006090. doi: 10.1371/journal.ppat.1006090. eCollection 2017 Jan.
2017 Jan degradation 6 5 GH20, GH38, GH125, GH92, GH29
PUL0207 enzyme activity assay N-glycan Streptococcus agalactiae 25605731
Metabolic fate of unsaturated glucuronic/iduronic acids from glycosaminoglycans: molecular identification and structure determination of streptococcal isomerase and dehydrogenase. J Biol Chem. 2015 Mar 6;290(10):6281-92. doi: 10.1074/jbc.M114.604546. Epub 2015 Jan 20.
2015 Mar 6 degradation 7 2 PL12, PL12_1, GH88
PUL0210 enzyme activity assay N-glycan Clostridium perfringens 25605731
Metabolic fate of unsaturated glucuronic/iduronic acids from glycosaminoglycans: molecular identification and structure determination of streptococcal isomerase and dehydrogenase. J Biol Chem. 2015 Mar 6;290(10):6281-92. doi: 10.1074/jbc.M114.604546. Epub 2015 Jan 20.
2015 Mar 6 degradation 13 3 PL8, GH88, PL12_1
PUL0211 enzyme activity assay, gene deletion mutant and growth assay, thin layer chromatography N-glycan Xanthomonas campestris pv. campestris 25586188, 25205095
The N-Glycan cluster from Xanthomonas campestris pv. campestris: a toolbox for sequential plant N-glycan processing. The plant pathogen Xanthomonas campestris pv. campestris exploits N-acetylglucosamine during infection. J Biol Chem. 2015 Mar 6;290(10):6022-36. doi: 10.1074/jbc.M114.624593. Epub 2015 Jan 13. mBio. 2014 Sep 9;5(5):e01527-14. doi: 10.1128/mBio.01527-14.
2015 Mar 6,2014 Sep 9 degradation 9 6 GH29, GH18, GH20, GH2, GH3, GH125, GH92, GH35
PUL0223 enzyme specificity assay, enzyme activity assay N-glycan Bacteroides thetaiotaomicron 23943617
Discovery of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans. J Biol Chem. 2013 Sep 20;288(38):27366-27374. doi: 10.1074/jbc.M113.469080. Epub 2013 Aug 13.
2013 Sep 20 degradation 9 4 GH92, GH130, GH163
PUL0555 gene deletion mutant and growth assay, qRT-PCR, microarray, enzyme activity assay N-glycan Bacteroides fragilis 25139987
Efficient utilization of complex N-linked glycans is a selective advantage for Bacteroides fragilis in extraintestinal infections. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12901-6. doi: 10.1073/pnas.1407344111. Epub 2014 Aug 19.
2014 Sep 2 degradation 9 5 GH154, GH2, GH20, GH88, PL0, PL33_1
PUL0556 gene deletion mutant and growth assay, qRT-PCR, microarray, enzyme activity assay N-glycan Bacteroides fragilis 25139987
Efficient utilization of complex N-linked glycans is a selective advantage for Bacteroides fragilis in extraintestinal infections. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12901-6. doi: 10.1073/pnas.1407344111. Epub 2014 Aug 19.
2014 Sep 2 degradation 7 1 GH18
PUL0574 enzyme activity assay alpha-mannoside, N-glycan Streptococcus pyogenes 16822234
Functional analysis of a group A streptococcal glycoside hydrolase Spy1600 from family 84 reveals it is a beta-N-acetylglucosaminidase and not a hyaluronidase. Biochem J. 2006 Oct 15;399(2):241-7. doi: 10.1042/BJ20060307.
2006 Oct 15 degradation 8 2 GH1, GH84, GH125, GH38