Basic Information | |
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Species | Selaginella moellendorffii |
Cazyme ID | 147086 |
Family | GT47 |
Protein Properties | Length: 378 Molecular Weight: 43777.2 Isoelectric Point: 9.2323 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 1 | 300 | 0 |
MYELPRKYNFGLFNRDGPAQEIPWKNLSNLPGPHTQGLKKQHSVEYWMTLDLLDEGGREFRAAQRVSDPGEADVFFVPYFASLSFNVFGVSMRDPETEHD KKLQVGMIEYLSKSPWYQRSGGRDHVLVLHHPNAFRFLKDRLNLSLLVVADFGRFPKGVAALHKDVVAPYSHMVPTYNGDDGTDPFEERTTLLFFQGRVK RKDDGVVRTQLAAILENQPRVHFEEGIATNFTVEQAMQGMRSSRFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDKIELPFEDELDYSEFSLFFSVDEAVR |
Full Sequence |
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Protein Sequence Length: 378 Download |
MYELPRKYNF GLFNRDGPAQ EIPWKNLSNL PGPHTQGLKK QHSVEYWMTL DLLDEGGREF 60 RAAQRVSDPG EADVFFVPYF ASLSFNVFGV SMRDPETEHD KKLQVGMIEY LSKSPWYQRS 120 GGRDHVLVLH HPNAFRFLKD RLNLSLLVVA DFGRFPKGVA ALHKDVVAPY SHMVPTYNGD 180 DGTDPFEERT TLLFFQGRVK RKDDGVVRTQ LAAILENQPR VHFEEGIATN FTVEQAMQGM 240 RSSRFCLHPA GDTPSSCRLF DAIVSHCVPV IVSDKIELPF EDELDYSEFS LFFSVDEAVR 300 PGFLLGALEK FSKRRWMKMW RRLKQVTRHF EYQHPSQRDD AVNMLWSQIH KKVPAMKLAM 360 HRAKRLKIQD WWKCKRL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-63 | 1 | 305 | 313 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Sequence Alignments (This image is cropped. Click for full image.) |
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