Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10015791 |
Family | GT47 |
Protein Properties | Length: 452 Molecular Weight: 52274.7 Isoelectric Point: 8.9346 |
Chromosome | Chromosome/Scaffold: 430 Start: 404866 End: 407051 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 70 | 385 | 0 |
PLNVYMYDLPRKFHVGMMDPAAGQENEPVTVENIPRWQKNAGVRKQHSVEYWLMVSLLSDGDGGGGREAVRVLDPEKADAFYVPFFSSLSFNTHGHNMTD PETEADRQLQVEIIDMLYKSKYWQRSGGRDHVIPMTHPNAFRFLRQELNASILIVVDFGRYPRSMSTLHKDVVAPYVHVVDTFTNDDVKDPYESRKTLIF FRGSTVRKDEGKVRAKLEKILAGQESVRYEQGRPTTHSIQESTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVVVSDKIELPYEDEIDYTKFALFFS DSKALKPGYLVDKLRN |
Full Sequence |
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Protein Sequence Length: 452 Download |
MEEIGRARSP KMYGKVIISV IFFLLLAFSY SIFIGSLDFR PYFFPRLPQL QQHSPEASPP 60 ADASSCEYKP LNVYMYDLPR KFHVGMMDPA AGQENEPVTV ENIPRWQKNA GVRKQHSVEY 120 WLMVSLLSDG DGGGGREAVR VLDPEKADAF YVPFFSSLSF NTHGHNMTDP ETEADRQLQV 180 EIIDMLYKSK YWQRSGGRDH VIPMTHPNAF RFLRQELNAS ILIVVDFGRY PRSMSTLHKD 240 VVAPYVHVVD TFTNDDVKDP YESRKTLIFF RGSTVRKDEG KVRAKLEKIL AGQESVRYEQ 300 GRPTTHSIQE STEGMRSSKF CLHPAGDTPS SCRLFDAIVS HCVPVVVSDK IELPYEDEID 360 YTKFALFFSD SKALKPGYLV DKLRNFPKER WLEMWRNLKN ISRHFEFEFP PAKGDAADML 420 WRQIRRKLPE VQLAVHRSHR LTVPDWWRRR R* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-65 | 69 | 386 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 12 | 428 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 12 | 447 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 38 | 451 | 27 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 70 | 447 | 1 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 12 | 450 | 1 | 434 | catalytic, putative [Ricinus communis] |