Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10003870 |
Family | GT47 |
Protein Properties | Length: 499 Molecular Weight: 57213.5 Isoelectric Point: 8.9251 |
Chromosome | Chromosome/Scaffold: 706 Start: 145438 End: 147011 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 103 | 420 | 0 |
KPLKVFMYDMPPEFHFELLDWKAEVNGSVWPDITKHIPGYPGGLNLQHSIEYWLTLDLLASEFPRIPRAGGAVRVKNSSDADVVFVPFFSSLSYNRFSKV NPHQKKSRNNVLQDKLVEYLTSQEEWKRSGGKDHVVMAHHPNSMLTARMKLWPAMFILSDFGRYPPNVANVEKDVIAPYKHIIKSYVNDSSEFDTRPTLL YFQGAIYRKDGGLARQELFYLLKDEKDVHFQFGSVKNDGIHKASIGMHSSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDDIELPYEDVLDYSEFCIFV KTSDAIKENYLINFIRSI |
Full Sequence |
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Protein Sequence Length: 499 Download |
MGEKRHGSWS IGTVAGKQVW WLFPFFTALF LFSWFSVLGS TAKPNFLDRA FLPTLTTLSV 60 LQNEISQPSA PSSTFRALLV DDDDATTSEI DNIVNCERSS SLKPLKVFMY DMPPEFHFEL 120 LDWKAEVNGS VWPDITKHIP GYPGGLNLQH SIEYWLTLDL LASEFPRIPR AGGAVRVKNS 180 SDADVVFVPF FSSLSYNRFS KVNPHQKKSR NNVLQDKLVE YLTSQEEWKR SGGKDHVVMA 240 HHPNSMLTAR MKLWPAMFIL SDFGRYPPNV ANVEKDVIAP YKHIIKSYVN DSSEFDTRPT 300 LLYFQGAIYR KDGGLARQEL FYLLKDEKDV HFQFGSVKND GIHKASIGMH SSKFCLNIAG 360 DTPSSNRLFD AIVSHCVPVI ISDDIELPYE DVLDYSEFCI FVKTSDAIKE NYLINFIRSI 420 KKEEWTRMWQ RLKEVEHLFQ FQYPSREGDA VQMIWQAVAR KVPGIKMKMH KSMRYSRFVS 480 NQKGGVSNRV IRTPKNFW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-54 | 101 | 420 | 330 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 1 | 498 | 1 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | NP_190126.1 | 0 | 1 | 498 | 1 | 475 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002319201.1 | 0 | 1 | 476 | 3 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325457.1 | 0 | 95 | 498 | 63 | 463 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 40 | 477 | 38 | 481 | catalytic, putative [Ricinus communis] |