Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 313939 |
Family | GT47 |
Protein Properties | Length: 479 Molecular Weight: 54219.1 Isoelectric Point: 8.9089 |
Chromosome | Chromosome/Scaffold: 1 Start: 16124547 End: 16126606 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 54 | 402 | 0 |
NGINVFVAELPRSLNYGLLDKYWSSSSPDSRIPSDPDHPTRKTHLPKPGKYPPYPENPLIKQYSAEYWIMGDLETSPEKRIGSFAKRVFSESDADVVFVP FFATLSAEMELGNGKGSFRKKNGNEDYQRQRQVLDFVKNTEAWKRSNGRDHVFVLTDPVAMWHVREEIALSILLVVDFGGWFRQDSKSSNGTSLPERIEH TQVSVIKDVIVPYTHLLPSLDLSQNQRRHSLLYFKGAKHRHRGGLIREKLWDLLVDEQGIVMEEGFPNATGREQSIIGMRNSEFCLHPAGDTPTSCRLFD AIQSLCIPVIVSDTIELPFEGIIDYSEFSVFVPVSDALTPKWLANHLRR |
Full Sequence |
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Protein Sequence Length: 479 Download |
MVPKIASMAT RPLCSLPYLF LSFSLLFVVS LLFFFSNSLI SNPNPRISHN TLQNGINVFV 60 AELPRSLNYG LLDKYWSSSS PDSRIPSDPD HPTRKTHLPK PGKYPPYPEN PLIKQYSAEY 120 WIMGDLETSP EKRIGSFAKR VFSESDADVV FVPFFATLSA EMELGNGKGS FRKKNGNEDY 180 QRQRQVLDFV KNTEAWKRSN GRDHVFVLTD PVAMWHVREE IALSILLVVD FGGWFRQDSK 240 SSNGTSLPER IEHTQVSVIK DVIVPYTHLL PSLDLSQNQR RHSLLYFKGA KHRHRGGLIR 300 EKLWDLLVDE QGIVMEEGFP NATGREQSII GMRNSEFCLH PAGDTPTSCR LFDAIQSLCI 360 PVIVSDTIEL PFEGIIDYSE FSVFVPVSDA LTPKWLANHL RRFSEREKET FRGRMAKVQT 420 VFVYDNGQGN GIGPIEPNGA VNHIWKKVQQ KVPMVKEAVI RERRKPAGAS VPLRCQCI* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-59 | 91 | 403 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 1 | 478 | 1 | 477 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 13 | 477 | 16 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 14 | 477 | 13 | 475 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 32 | 477 | 5 | 448 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 40 | 477 | 39 | 477 | catalytic, putative [Ricinus communis] |