Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr4g077920.1 |
Family | GT47 |
Protein Properties | Length: 503 Molecular Weight: 57084.6 Isoelectric Point: 9.5975 |
Chromosome | Chromosome/Scaffold: 4 Start: 25481747 End: 25487157 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 112 | 422 | 0 |
LKVYVYNMPNKFTYDLLLLFRNTYRDTSNLTSNGSPVHRLIEQHSIDYWLWADLIAPESERLLKSVVRVHRQEEADFFYIPFFTTISFFLLEKQQCKALY REALKWITDQPAWKRSGGRDHILPVHHPWSFKTVRRYVKKAIWLLPDMDSTGNWYKPGQVYLEKDLILPYVANVDFCDATCLSEINPKRNTLLFFRGRLK RNAGGKIRSKLVDQLRGADGVVIEEGTSGEGGKEAAQNGMRKSLFCLNPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYRKIALFVSSNDALK PSWLLKYLKDI |
Full Sequence |
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Protein Sequence Length: 503 Download |
MAGKQISRSK SRIILLSLSL LGFSLLIFLS SLSPLRTTSP SSTHFHLPTT SHTSFVTSLE 60 HFLKTHPSPS LPDDTPHKPL TDQHVTNLDN SVFHSETNRL NSDPFYPISL PLKVYVYNMP 120 NKFTYDLLLL FRNTYRDTSN LTSNGSPVHR LIEQHSIDYW LWADLIAPES ERLLKSVVRV 180 HRQEEADFFY IPFFTTISFF LLEKQQCKAL YREALKWITD QPAWKRSGGR DHILPVHHPW 240 SFKTVRRYVK KAIWLLPDMD STGNWYKPGQ VYLEKDLILP YVANVDFCDA TCLSEINPKR 300 NTLLFFRGRL KRNAGGKIRS KLVDQLRGAD GVVIEEGTSG EGGKEAAQNG MRKSLFCLNP 360 AGDTPSSARL FDAIVSGCIP VIVSDELELP FEGILDYRKI ALFVSSNDAL KPSWLLKYLK 420 DIRSAHIKEM QQNLAKYSRH FLYSSPAQPL GPEDLVWKMM AGKVVNIKLH SRRSQRVVEG 480 SRNVCTCECR PGNITNTVST IS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-69 | 111 | 422 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAY76230.1 | 0 | 33 | 486 | 46 | 488 | hypothetical protein OsI_04166 [Oryza sativa Indica Group] |
RefSeq | NP_197191.1 | 0 | 1 | 489 | 1 | 495 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 52 | 496 | 63 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 31 | 498 | 42 | 504 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 53 | 496 | 58 | 503 | catalytic, putative [Ricinus communis] |