| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi5g25660.1 |
| Family | GT47 |
| Protein Properties | Length: 461 Molecular Weight: 51521.3 Isoelectric Point: 8.6733 |
| Chromosome | Chromosome/Scaffold: 5 Start: 26869277 End: 26872263 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 41 | 384 | 0 |
| RRLSVYVTDLPRALNHGLLDLYWSLPTADARIPASSDPDHPPPRAHPPYPASPLIRQYSAEYWLLASLLRPGPASSSAVSVVADWTEADVVFVPFFATLS AELELGWGATKGAFRRKEGNADYRRQREVVDRVTAHPAWRRSGGRDHVFVLTDPMAMWHVRAEIAPAILLVVDFGGWYKLDSKSAGSNSSHMIQHTQVSL LKDVIIPYTHLLPTLQLSENMDRPTLLYFKGAKHRHRGGLVREKLWDVMINEPGVVMEEGFPNATGREQSIKGMRTSEFCLHPAGDTPSSCRLFDAVASL CIPVIVSDDIELPFEGMIDYTEFSIFVSVGNAMRPKWLASYLKT | |||
| Full Sequence |
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| Protein Sequence Length: 461 Download |
| MKPPALLAVL LLLSLSFLLF LLRPTSPPFL LSAQTSGTDR RRLSVYVTDL PRALNHGLLD 60 LYWSLPTADA RIPASSDPDH PPPRAHPPYP ASPLIRQYSA EYWLLASLLR PGPASSSAVS 120 VVADWTEADV VFVPFFATLS AELELGWGAT KGAFRRKEGN ADYRRQREVV DRVTAHPAWR 180 RSGGRDHVFV LTDPMAMWHV RAEIAPAILL VVDFGGWYKL DSKSAGSNSS HMIQHTQVSL 240 LKDVIIPYTH LLPTLQLSEN MDRPTLLYFK GAKHRHRGGL VREKLWDVMI NEPGVVMEEG 300 FPNATGREQS IKGMRTSEFC LHPAGDTPSS CRLFDAVASL CIPVIVSDDI ELPFEGMIDY 360 TEFSIFVSVG NAMRPKWLAS YLKTISKQQK DEFRRNLAKV QHIFEYENSH HGSTGSAPED 420 GAVNHIWKKI HQKLPMIQEA IIREKRKPEG ASIPLRCHCT * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-65 | 40 | 385 | 358 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAE02830.1 | 0 | 23 | 460 | 23 | 464 | OSJNBa0043A12.35 [Oryza sativa (japonica cultivar-group)] |
| GenBank | EEC78225.1 | 0 | 23 | 460 | 23 | 452 | hypothetical protein OsI_17865 [Oryza sativa Indica Group] |
| RefSeq | NP_001137073.1 | 0 | 23 | 460 | 24 | 458 | hypothetical protein LOC100217246 [Zea mays] |
| RefSeq | XP_002448739.1 | 0 | 23 | 460 | 24 | 456 | hypothetical protein SORBIDRAFT_06g032380 [Sorghum bicolor] |
| RefSeq | XP_002533317.1 | 0 | 43 | 460 | 55 | 478 | catalytic, putative [Ricinus communis] |
