Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10013787 |
Family | GT47 |
Protein Properties | Length: 527 Molecular Weight: 59680.7 Isoelectric Point: 9.208 |
Chromosome | Chromosome/Scaffold: 1168 Start: 476845 End: 479359 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 116 | 426 | 0 |
LRVYVYRMPPKFTYDLLRLFDSTYHDTSNLTSNGSPVHRLIEQHSVDYWLWADLIAPQSERLLKSVIRVDRQEDADLFYIPFFTTISFFLLDKQECKPLY REALKWVTDQPAWKRSQGRDHILPVHHPWSFKSVRRYMKNAIWLLPDMDSTGNWYKPGQVYLEKDLILPYVANLDLCDATCLTEYESKRTTLLFFRGRLK RNAGGKIRAKLVSQLSGVEGVVIQEGTAGERGKELAQNGMRKSIFCLNPAGDTPSSARLFDAIVSGCIPVIISDELELPFEGILDYRKIALFVSSSDASE PGWLIKFLRSI |
Full Sequence |
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Protein Sequence Length: 527 Download |
MATKFSSRSR SPIFLFSIFI AVAVSLLLLT FIFSSSPPTL HPSPPGLSTS PTSIRPETSF 60 VTSLRNFLIS RPSDGDVLIS GDQLAPSSTV LDDAVFDRQT DRMYQGDPIY PPDFPLRVYV 120 YRMPPKFTYD LLRLFDSTYH DTSNLTSNGS PVHRLIEQHS VDYWLWADLI APQSERLLKS 180 VIRVDRQEDA DLFYIPFFTT ISFFLLDKQE CKPLYREALK WVTDQPAWKR SQGRDHILPV 240 HHPWSFKSVR RYMKNAIWLL PDMDSTGNWY KPGQVYLEKD LILPYVANLD LCDATCLTEY 300 ESKRTTLLFF RGRLKRNAGG KIRAKLVSQL SGVEGVVIQE GTAGERGKEL AQNGMRKSIF 360 CLNPAGDTPS SARLFDAIVS GCIPVIISDE LELPFEGILD YRKIALFVSS SDASEPGWLI 420 KFLRSISRAQ IKELQANLAK YSRHFVYSSP AQPFGPEDLV WRMMFAYVLD NPNGFVCKQM 480 GGKMVNIKLH IRRSQRVVRE SRSICTCDCR RPASNVTLPG QITKSA* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-69 | 115 | 426 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAY76230.1 | 0 | 43 | 506 | 45 | 488 | hypothetical protein OsI_04166 [Oryza sativa Indica Group] |
RefSeq | NP_197191.1 | 0 | 8 | 511 | 16 | 497 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 53 | 519 | 59 | 513 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 39 | 511 | 38 | 497 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 53 | 519 | 53 | 504 | catalytic, putative [Ricinus communis] |