Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_013_00618.4 |
Family | GT47 |
Protein Properties | Length: 513 Molecular Weight: 58705.6 Isoelectric Point: 9.2463 |
Chromosome | Chromosome/Scaffold: 13 Start: 4055199 End: 4060327 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 125 | 436 | 0 |
VLKVYVYEMPAKFTYDLLWLFRNTYRDTVNLTSNGSPVHRLIEQHSIDYWLWADLIAPESERILKNVIRVDRQEDADLFYIPFFTTISFFLLEKQQCKAL YREALKWVTDQPAWKRSEGRDHILPVHHPWSFKSVRRFMKKAIWLLPDMDSTGNWYKPGEVWLEKDLILPYVPNVEVCDANCLSKSESKRDTLLFFRGRL KRNAGGKIRSKLVMELNGSEGVIIEEGTSGESGKEAATNGMRRSIFCLNPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYRKIALFVSSSDAV EPGKLLTFLKSI |
Full Sequence |
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Protein Sequence Length: 513 Download |
MAGRALNSRE REKSFSFSFR PASTSTFFLF ALSLIAIAFF FFFSSSFHFI PNQNPKTSSH 60 SSLPNSNPEY SFVTCLEKFL TSRSRIPKSE SISKDSDEVV VNKLDDLMWN REMERLDEGL 120 FDPSVLKVYV YEMPAKFTYD LLWLFRNTYR DTVNLTSNGS PVHRLIEQHS IDYWLWADLI 180 APESERILKN VIRVDRQEDA DLFYIPFFTT ISFFLLEKQQ CKALYREALK WVTDQPAWKR 240 SEGRDHILPV HHPWSFKSVR RFMKKAIWLL PDMDSTGNWY KPGEVWLEKD LILPYVPNVE 300 VCDANCLSKS ESKRDTLLFF RGRLKRNAGG KIRSKLVMEL NGSEGVIIEE GTSGESGKEA 360 ATNGMRRSIF CLNPAGDTPS SARLFDAIVS GCIPVIVSDE LELPFEGILD YRKIALFVSS 420 SDAVEPGKLL TFLKSISPSN IKKMRANLAK YMKHFLYSSP AQPLGPEDLA WRMIAGKLAN 480 IKLHIRRSQR VVKESRRLCT CECKRANVTS LP* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-68 | 123 | 436 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20132.1 | 0 | 133 | 510 | 1 | 378 | unnamed protein product [Vitis vinifera] |
GenBank | EAY76230.1 | 0 | 58 | 500 | 51 | 488 | hypothetical protein OsI_04166 [Oryza sativa Indica Group] |
RefSeq | XP_002285599.1 | 0 | 68 | 510 | 62 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 59 | 511 | 42 | 503 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 58 | 510 | 42 | 503 | catalytic, putative [Ricinus communis] |