Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g011195m |
Family | GT47 |
Protein Properties | Length: 492 Molecular Weight: 56326.4 Isoelectric Point: 9.5848 |
Chromosome | Chromosome/Scaffold: 00331 Start: 113428 End: 117196 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 100 | 415 | 0 |
VLKVYMYDLPPQFHFELLDWKSQGGSVWPDIRTRIPHYPGGLNLQHSIEYWLTLDLLASELPDNPSACGAIRVHNSSGADIIFVPFFSSLSYNKYSKKSP QQNKINNKVLQEKVVRFVTSQEEWKRSGGRDHLIVAHHPNSMLDARTKLWPAMFILADFGRYPPHIANVDKDVIAPYKHMVKSYVNDTSEFDSRPILLYF QGAIYRKDGGSVRQELFYLLKDEKDVHFSFGSVQKNGIHQASQGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPYEDILDYSEFCIFVRT SDAVKGNFLINLVRNI |
Full Sequence |
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Protein Sequence Length: 492 Download |
MGERNASSFG FISRNFLFFL LAITSILFSL SWFFVLRSTG SPHFVDHSLL SNSAPPSIID 60 NGSSKESKPK SLDHVKNSVQ EEELPQKKKD IKCNKNKKGV LKVYMYDLPP QFHFELLDWK 120 SQGGSVWPDI RTRIPHYPGG LNLQHSIEYW LTLDLLASEL PDNPSACGAI RVHNSSGADI 180 IFVPFFSSLS YNKYSKKSPQ QNKINNKVLQ EKVVRFVTSQ EEWKRSGGRD HLIVAHHPNS 240 MLDARTKLWP AMFILADFGR YPPHIANVDK DVIAPYKHMV KSYVNDTSEF DSRPILLYFQ 300 GAIYRKDGGS VRQELFYLLK DEKDVHFSFG SVQKNGIHQA SQGMHSSKFC LNIAGDTPSS 360 NRLFDAIASH CVPVIISDEI ELPYEDILDY SEFCIFVRTS DAVKGNFLIN LVRNIKKDEW 420 THMRDRLKEV QRFFEFQFPS KEGDAVQMIW QAVARKVPAM RRNIHKSRRF SRTVTGKEEG 480 LKLIPSQPNF W* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-50 | 101 | 415 | 330 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 1 | 491 | 1 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
EMBL | CAN68950.1 | 0 | 1 | 491 | 1 | 488 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268382.1 | 0 | 1 | 491 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 1 | 471 | 3 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 1 | 486 | 1 | 495 | catalytic, putative [Ricinus communis] |