Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10005684 |
Family | GT47 |
Protein Properties | Length: 598 Molecular Weight: 68733.2 Isoelectric Point: 10.5693 |
Chromosome | Chromosome/Scaffold: 911 Start: 134012 End: 136722 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 190 | 509 | 0 |
QKQLKVFMYDMPPEFHFSLLEWKPEENGNVWPDVTAHIPGYPGGLNLQHSIEYWLTLDLLASEFPHIPRGSSAVRVRNSSDADVVFVPFFSSLSYNRYSK VDPHQKKSRNNLLQDKLVRYLTSQEEWKRSGGRDHLVMAHHPNSMLSARMKLWPAMFVLSDFGRYPPNVANVEKDVIAPYKHVVKSYVDDTSEFDTRPTL LYFQGAIYRKDGGLARQELFYLLKDEKDVHFQFGSVKKDGIHNASRGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPYEDVLDYSEFCIF VKTSDAVRDKKFLINFIRSI |
Full Sequence |
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Protein Sequence Length: 598 Download |
MALLLLHQKP TSYPSANSLP PNLLKKTRRN KHHLSFRFLP LFIKTSESKG LLTSESKVSI 60 RKWRGDNTEQ SILRCRQGRR RERGKKISPM GSSIARKLVF CMFPFISAAV MLSSWVFVVR 120 SFSAGRPSFL DRAFLPAVTT LSAVETESTT AMPRPSRARA ILVDREIAGR IEKNIVKVPK 180 CSDGRKTRRQ KQLKVFMYDM PPEFHFSLLE WKPEENGNVW PDVTAHIPGY PGGLNLQHSI 240 EYWLTLDLLA SEFPHIPRGS SAVRVRNSSD ADVVFVPFFS SLSYNRYSKV DPHQKKSRNN 300 LLQDKLVRYL TSQEEWKRSG GRDHLVMAHH PNSMLSARMK LWPAMFVLSD FGRYPPNVAN 360 VEKDVIAPYK HVVKSYVDDT SEFDTRPTLL YFQGAIYRKD GGLARQELFY LLKDEKDVHF 420 QFGSVKKDGI HNASRGMHSS KFCLNIAGDT PSSNRLFDAI ASHCVPVIIS DEIELPYEDV 480 LDYSEFCIFV KTSDAVRDKK FLINFIRSIK KEEWTRMWNR LKEVETLFRF QYPSKEGDAV 540 QMIWQAVARK VPGVKMKIHK SRRYSRFGNG DGNANVIKPR YSRGSSSRHI RTPKNFW* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-55 | 189 | 509 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 123 | 597 | 39 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | XP_002268382.1 | 0 | 123 | 597 | 38 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 94 | 565 | 15 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325457.1 | 0 | 193 | 597 | 73 | 463 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 123 | 569 | 38 | 485 | catalytic, putative [Ricinus communis] |