Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 477609 |
Family | GT47 |
Protein Properties | Length: 496 Molecular Weight: 56527.6 Isoelectric Point: 9.7663 |
Chromosome | Chromosome/Scaffold: 3 Start: 1144824 End: 1147163 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 120 | 433 | 0 |
RRPLKVYMYDMSPEFHFGLLGWKPDRNDVVWPDIRVIVPHHPGGLNLQHSVEYWLTLDLLFSELPEDSRSSRAAVRVKNSSEADVVFVPFFSSLSYNRFS KVNQKQKKSQDKELQVNVVKYVTSQKEWKISGGKDHVIMAHHPNSMSTARHKLYPAMFVVADFGRYSPHVANIDKDIVAPYKHLVPSYANDTSGFDGRPI LLYFQGAIYRKAGGFVRQELYKDVHFSFGSVRNHGITKAGEGMRSSKFCLNIAGDTPSSNRLFDAIASHCIPVIISDDIELPYEDVLNYNEFCLFVRSSD ALKKGFLMGLVKSI |
Full Sequence |
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Protein Sequence Length: 496 Download |
MGERSNSRYL GVIITRKSII FLSISILTVL SWFLIFSSTN PNRVLDYISV SESTDVPLII 60 IKNSNTSPQN NAISPNPQNR EGAQTEGPDN ENRGGTKTES SMNQNRVKTL RCIQKVSPSR 120 RPLKVYMYDM SPEFHFGLLG WKPDRNDVVW PDIRVIVPHH PGGLNLQHSV EYWLTLDLLF 180 SELPEDSRSS RAAVRVKNSS EADVVFVPFF SSLSYNRFSK VNQKQKKSQD KELQVNVVKY 240 VTSQKEWKIS GGKDHVIMAH HPNSMSTARH KLYPAMFVVA DFGRYSPHVA NIDKDIVAPY 300 KHLVPSYAND TSGFDGRPIL LYFQGAIYRK AGGFVRQELY KDVHFSFGSV RNHGITKAGE 360 GMRSSKFCLN IAGDTPSSNR LFDAIASHCI PVIISDDIEL PYEDVLNYNE FCLFVRSSDA 420 LKKGFLMGLV KSIGRDEYNK MWLRLKEVER YFDLRFPTKD DEGDYAVQMI WEAVARKAPL 480 VKMKVHRFQR YTKPF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-52 | 119 | 433 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 57 | 493 | 56 | 490 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | NP_187015.1 | 0 | 1 | 495 | 1 | 499 | EDA5 (embryo sac development arrest 5); catalytic [Arabidopsis thaliana] |
RefSeq | NP_190126.1 | 0 | 111 | 492 | 67 | 454 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002319201.1 | 0 | 1 | 492 | 3 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 82 | 495 | 68 | 483 | catalytic, putative [Ricinus communis] |