| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra008584 |
| Family | GT47 |
| Protein Properties | Length: 452 Molecular Weight: 51589.2 Isoelectric Point: 8.8771 |
| Chromosome | Chromosome/Scaffold: 10 Start: 12924920 End: 12927204 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 108 | 384 | 0 |
| VKVYVYEMPKKFTFDLLWLFHNTYKETSNATSNGSPVHRLIEQHSVDYWLWADLISPESERRLKSVVRVHKQEEADFYYVPFFTTISFFLLEKQQCKALY RASEGRDHIFPIHHPWSFKTVRKFVKNAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDLCDAKCLSESAPMRTTLLFFRGRLKRNAGGKIRAKLGS ELSGVKDVIITEGTAGEGGKLAAQEGMRRSLFCLCPAGDTPSSARLFDAIVSGCIPVVVSDELELPFEGILDYRKYS | |||
| Full Sequence |
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| Protein Sequence Length: 452 Download |
| MAGKQQNHHR TLPRFRSKTI IFTLIISSFS LLVILFTFPS SPNPPVRIET SFVASLEQFL 60 IHNAPKLNPP SRDDTVRGEK EDDDVRKLDE MVFERENRLL DEDPVYPVKV YVYEMPKKFT 120 FDLLWLFHNT YKETSNATSN GSPVHRLIEQ HSVDYWLWAD LISPESERRL KSVVRVHKQE 180 EADFYYVPFF TTISFFLLEK QQCKALYRAS EGRDHIFPIH HPWSFKTVRK FVKNAIWLLP 240 DMDSTGNWYK PGQVSLEKDL ILPYVPNVDL CDAKCLSESA PMRTTLLFFR GRLKRNAGGK 300 IRAKLGSELS GVKDVIITEG TAGEGGKLAA QEGMRRSLFC LCPAGDTPSS ARLFDAIVSG 360 CIPVVVSDEL ELPFEGILDY RKYSRHFLYS SPAQPLGPED LTWRMIAGKL VNIKLHTRRS 420 QRVVNGSRSI CRCDCWRPNS TASNSLSHLL S* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-55 | 107 | 384 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20132.1 | 0 | 115 | 442 | 1 | 378 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197191.1 | 0 | 1 | 437 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 49 | 442 | 63 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 40 | 442 | 49 | 502 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 41 | 442 | 49 | 503 | catalytic, putative [Ricinus communis] |
