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Browse anti-prokaryotic immune system families by Defense system

AD families AD genes Defense system CLAN ID Phages/MGEs References Description
APIS005 Gad1 Gabija CLAN004 phi3T of B. subtilis Yirmiya et al., 2023 Antine et al., 2023 Gad1 forms an octameric web that encases the GajAB complex and inhibits DNA recognition and cleavage.
APIS008 Gad2 Gabija CLAN007 SPbetaL7 of B. subtilis Yirmiya et al., 2023 Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1.
APIS046 CLAN004
APIS053 CLAN004
APIS056 CLAN007
APIS057 CLAN004
APIS059 CLAN007 Pseudoalteromonas phage HM1
APIS065 CLAN004 Shewanella sp. phage 1/4
APIS068 CLAN004
APIS071 CLAN004
APIS083 CLAN004 Clostridioides phage ES-S-0107-01
APIS088 CLAN004
APIS089 CLAN007