Basic Information | |
---|---|
Species | Ricinus communis |
Cazyme ID | 28223.m000097 |
Family | GT47 |
Protein Properties | Length: 316 Molecular Weight: 37085.2 Isoelectric Point: 7.8022 |
Chromosome | Chromosome/Scaffold: 28223 Start: 32692 End: 33710 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 52 | 298 | 0 |
CFGRYIYIHDLPGEFNEDLLKHCQFLSEWSNMCSLISNFGLGPGLRNPDRVFSNTGWYETNQFMLEVIFHNRMKQYKCLTNDSSLASAIFVPYYAGLDVA RYLWNSHTEMKDYYSLDLVKWLTEKPEWKRMWGRDHFLVAGRITWDFRRLTDDNSDWGNKLMLLPESRNMTLLTIESSPWHANDFAIPYPTYFHPSSDKE VFGWQNRMRRIKRRFLFSFAGAPRPNITESIRGEIIRQCQATRRKCK |
Full Sequence |
---|
Protein Sequence Length: 316 Download |
MHLTENIEAQ SANKDFVKDN GIERKVDSVP KGEKKIEQLI VENGSDSDSE SCFGRYIYIH 60 DLPGEFNEDL LKHCQFLSEW SNMCSLISNF GLGPGLRNPD RVFSNTGWYE TNQFMLEVIF 120 HNRMKQYKCL TNDSSLASAI FVPYYAGLDV ARYLWNSHTE MKDYYSLDLV KWLTEKPEWK 180 RMWGRDHFLV AGRITWDFRR LTDDNSDWGN KLMLLPESRN MTLLTIESSP WHANDFAIPY 240 PTYFHPSSDK EVFGWQNRMR RIKRRFLFSF AGAPRPNITE SIRGEIIRQC QATRRKCKML 300 ECASAFRGFI YKAIDI |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-41 | 51 | 293 | 255 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN64889.1 | 0 | 15 | 303 | 262 | 550 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002280815.1 | 0 | 15 | 303 | 55 | 343 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002301846.1 | 0 | 7 | 302 | 71 | 373 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
RefSeq | XP_002313430.1 | 0 | 35 | 305 | 123 | 393 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
RefSeq | XP_002533095.1 | 0 | 1 | 316 | 1 | 316 | hypothetical protein RCOM_0203350 [Ricinus communis] |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
GR934411 | 258 | 45 | 302 | 0 |
EG389479 | 258 | 45 | 302 | 0 |
EY724166 | 237 | 54 | 290 | 0 |
AM717781 | 249 | 41 | 289 | 0 |
FY452442 | 238 | 45 | 282 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|