Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.140650.1 |
Family | GT47 |
Protein Properties | Length: 563 Molecular Weight: 64506.7 Isoelectric Point: 7.6918 |
Chromosome | Chromosome/Scaffold: 01071 Start: 610683 End: 612443 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 105 | 445 | 0 |
GGRYIFVHDLPSRFNEDMLKECKSLSLWTNMCKFTTNAGLGPPLENVEGVFSDTGWYATNQFAVDVIFSNRMKQYDCLTKDSSIAAAFFVPFYAGFDIAR YLWGYNISTRDRASLDLVNWLEKRPEWGIMGGRDHFLVAGRITWDFRRLSEEEKDWGNKLLFLPAAKNMSMLVVESSPWNANDFGIPYPTYFHPAKDSDV FIWQDRMRKLERKWVFSFAGAPRPDNPKSIRGQIIDQCKSSKVCKLLECDFGESKCHSPSSIMQMFQSSLFCLQPQGDSYTRRSAFDAMLAGCIPVFFHP GSAYTQYTWHLPKNFTRYSVFIPEDDIRKRNISIEERLAQI |
Full Sequence |
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Protein Sequence Length: 563 Download |
MRRRPVVIAP LEHMERGAGK NQNSRLCFLA LLSAFFWILL LYFHFVVLGG HSVDESIRLS 60 PEDGPVNLPV VRKFAPSRVV DAPKIDTFPF VKALKTVENK SDPCGGRYIF VHDLPSRFNE 120 DMLKECKSLS LWTNMCKFTT NAGLGPPLEN VEGVFSDTGW YATNQFAVDV IFSNRMKQYD 180 CLTKDSSIAA AFFVPFYAGF DIARYLWGYN ISTRDRASLD LVNWLEKRPE WGIMGGRDHF 240 LVAGRITWDF RRLSEEEKDW GNKLLFLPAA KNMSMLVVES SPWNANDFGI PYPTYFHPAK 300 DSDVFIWQDR MRKLERKWVF SFAGAPRPDN PKSIRGQIID QCKSSKVCKL LECDFGESKC 360 HSPSSIMQMF QSSLFCLQPQ GDSYTRRSAF DAMLAGCIPV FFHPGSAYTQ YTWHLPKNFT 420 RYSVFIPEDD IRKRNISIEE RLAQISPEQL KLMQEEVISM IPRLVYADPR SKLETLKDAF 480 DVSVQAIINK VTKLRKDIIE GHTDDNFIEE NSWKYALLED GQREVGPHEW DPFFSKPKDG 540 DSGDTSAKAA KNSWKNEQRD KS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-70 | 103 | 445 | 358 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACY08857.1 | 0 | 1 | 562 | 1 | 617 | xyloglucan galactosyltransferase [Eucalyptus grandis] |
DDBJ | BAE98519.1 | 0 | 1 | 562 | 7 | 618 | hypothetical protein [Arabidopsis thaliana] |
RefSeq | XP_002269766.1 | 0 | 1 | 549 | 59 | 652 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002301846.1 | 0 | 14 | 562 | 1 | 585 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
RefSeq | XP_002468517.1 | 0 | 1 | 562 | 1 | 599 | hypothetical protein SORBIDRAFT_01g047270 [Sorghum bicolor] |