Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna06576.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 495 Molecular Weight: 56574.4 Isoelectric Point: 7.2563 |
Chromosome | Chromosome/Scaffold: 4 Start: 17180655 End: 17182139 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 71 | 408 | 0 |
SCSGRYVYIHDDLPSKFNSDLLNNCKLLTRGTDKPNLCPYFENWGFGPAIENTEGVLANTSWFSTNQFTLEVIFHNKMKQYKCLTKNSTLASAIYVPFYA GLDASLHLWDSNLTVRDASARDLNDWLSKRPEWKTMWGRDHFLVGGRISWDFRRQTDEISDWGSKLRFLPESLNMSMLSVEGSSWRNDYAIPYPTNFHPA KDSDVVQWQNRMRKLERPHFFTFVGAPRPDQQNSIRGKIIDQCLASSVGKLVDCSSGGIKCDNPASVMRVFQSSVYCLQPTGDSYTRKSAFDSILAGCIP VFFHPGTAYSQYLWHLPKNHTKYSVFIPVRYVEDLKEG |
Full Sequence |
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Protein Sequence Length: 495 Download |
MEKPLIPKCS QDLWFGILIS FLFCFVFLSF DYSTFWGVNN GASLLVNKQN HPVGFVKNQT 60 VLSTTHLIPD SCSGRYVYIH DDLPSKFNSD LLNNCKLLTR GTDKPNLCPY FENWGFGPAI 120 ENTEGVLANT SWFSTNQFTL EVIFHNKMKQ YKCLTKNSTL ASAIYVPFYA GLDASLHLWD 180 SNLTVRDASA RDLNDWLSKR PEWKTMWGRD HFLVGGRISW DFRRQTDEIS DWGSKLRFLP 240 ESLNMSMLSV EGSSWRNDYA IPYPTNFHPA KDSDVVQWQN RMRKLERPHF FTFVGAPRPD 300 QQNSIRGKII DQCLASSVGK LVDCSSGGIK CDNPASVMRV FQSSVYCLQP TGDSYTRKSA 360 FDSILAGCIP VFFHPGTAYS QYLWHLPKNH TKYSVFIPVR YVEDLKEGLI EKTLVGISKE 420 KELEMREEVI RLIPKLVYAD PMSRLETEDA FDLSVKGILE TIENVRKTIR EGRDPSIGFA 480 DEDSYKYTFP KTLE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-62 | 71 | 409 | 353 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |