Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.003G006800.1 |
Family | GT47 |
Protein Properties | Length: 460 Molecular Weight: 52501.8 Isoelectric Point: 7.5622 |
Chromosome | Chromosome/Scaffold: 03 Start: 656625 End: 658665 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 67 | 400 | 0 |
RPLFYILPLPSRFNLQLLHNCQNLNIYTNMCPHVANNGLGQPLSTPSWYATHQFIGEMILHARLENHPCRTSDPHAARLFYVPFYGGLHASSVFREQNLT LRDALAVDLVDFVQSQPWWQRHSGKDHFVALGRTAWDFMRTEDGEDFGANIFLNLPSVGNMSVLTVERNPWHGHNQFAIPYPSYFHPKTLSDMLTWQNTV RQRPRPHLFSFVGGTRPNLAKAKVRDHIITQCDTSERCVLVRCASGDARCHDPMQVLEVMSKSTFCLQAPGDSFTRRSTFDSILAGCIPVFFSEHTAYTQ YVWYFPTERDTYSVFIDEREVNEGKKRIEDVLVG |
Full Sequence |
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Protein Sequence Length: 460 Download |
MFFRKPSPLH SLPSPTPPSF SKSKHPHNHK LTYTLFFSLF LLPWLLLLHR HLTPSQKHAA 60 TPCHPSRPLF YILPLPSRFN LQLLHNCQNL NIYTNMCPHV ANNGLGQPLS TPSWYATHQF 120 IGEMILHARL ENHPCRTSDP HAARLFYVPF YGGLHASSVF REQNLTLRDA LAVDLVDFVQ 180 SQPWWQRHSG KDHFVALGRT AWDFMRTEDG EDFGANIFLN LPSVGNMSVL TVERNPWHGH 240 NQFAIPYPSY FHPKTLSDML TWQNTVRQRP RPHLFSFVGG TRPNLAKAKV RDHIITQCDT 300 SERCVLVRCA SGDARCHDPM QVLEVMSKST FCLQAPGDSF TRRSTFDSIL AGCIPVFFSE 360 HTAYTQYVWY FPTERDTYSV FIDEREVNEG KKRIEDVLVG IEEKEVEKMR EVVIGLIPKL 420 TYTHPNASGD VGFEDVVDVA LQHLSHLLDE SRSFGSADI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-63 | 64 | 387 | 338 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 71 | 445 | 74 | 444 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 71 | 445 | 74 | 444 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 51 | 445 | 106 | 496 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 71 | 444 | 8 | 391 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 53 | 444 | 12 | 412 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CA910348 | 217 | 232 | 448 | 0 |
DY298787 | 314 | 98 | 401 | 0 |
DY265125 | 332 | 71 | 391 | 0 |
FC899396 | 311 | 71 | 372 | 0 |
FC884199 | 295 | 98 | 383 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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