Basic Information | |
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Species | Oryza sativa |
Cazyme ID | LOC_Os12g38450.1 |
Family | GT47 |
Protein Properties | Length: 527 Molecular Weight: 58563.4 Isoelectric Point: 9.4604 |
Chromosome | Chromosome/Scaffold: 12 Start: 23602840 End: 23604420 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 97 | 453 | 0 |
CAGRYVYMHELPSRFNSDLLRDCRTLSEWTDMCRHVANGGIGPRLPPAARGGVLPATGWYDTNQFTLEVIFHARMRRYGCLTADASRAAAVYVPYYPGLD VGRYLWGFSNGVRDLLAEDLAEWLRGTPAWAAHGGRDHFLVGGRIAWDFRREDGGGEGSQWGSRLLLLPEAMNMTALVIEASPWHRRTDVAVPYPTYFHP WRPSDVSSWQRDARRARRPWLFAFAGAGRGNGDDHDRHHGGGVVRDRVIAQCARSRRCGLLRCGARGRRDDCYDPGNVMRLFKSAAFCLQPRGDSYTRRS VFDAILAGCVPVFFHPGSAYTQYRWHLPRDHAAYSVFVPEDGVRNGTVRLEDVLRRV |
Full Sequence |
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Protein Sequence Length: 527 Download |
MDGSHGSAAA LRATGRCLAP LIIPASCVVW VLFFFPSPSP DVAVRRDGFL PAVTLPVQRA 60 GDTPPPPPII DASPPPPSTS PPPPPPRRGR PARRDRCAGR YVYMHELPSR FNSDLLRDCR 120 TLSEWTDMCR HVANGGIGPR LPPAARGGVL PATGWYDTNQ FTLEVIFHAR MRRYGCLTAD 180 ASRAAAVYVP YYPGLDVGRY LWGFSNGVRD LLAEDLAEWL RGTPAWAAHG GRDHFLVGGR 240 IAWDFRREDG GGEGSQWGSR LLLLPEAMNM TALVIEASPW HRRTDVAVPY PTYFHPWRPS 300 DVSSWQRDAR RARRPWLFAF AGAGRGNGDD HDRHHGGGVV RDRVIAQCAR SRRCGLLRCG 360 ARGRRDDCYD PGNVMRLFKS AAFCLQPRGD SYTRRSVFDA ILAGCVPVFF HPGSAYTQYR 420 WHLPRDHAAY SVFVPEDGVR NGTVRLEDVL RRVSAARVAA MREQVIRMIP TVVYRDPRAP 480 SARGFTDAID VAVDGVIERV RRIKQGLPPG GDDDDDHRWD AYFDTQ* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-50 | 97 | 437 | 351 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0008150 | biological_process |
GO:0008152 | metabolic process |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA99677.1 | 0 | 1 | 526 | 1 | 526 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
GenBank | EAY83600.1 | 0 | 1 | 526 | 1 | 526 | hypothetical protein OsI_38822 [Oryza sativa Indica Group] |
GenBank | EEE53469.1 | 0 | 1 | 526 | 1 | 487 | hypothetical protein OsJ_36598 [Oryza sativa Japonica Group] |
RefSeq | XP_002280815.1 | 0 | 88 | 524 | 84 | 522 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002442366.1 | 0 | 7 | 526 | 6 | 586 | hypothetical protein SORBIDRAFT_08g018880 [Sorghum bicolor] |