Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi3g28006.1 |
Family | GT47 |
Protein Properties | Length: 515 Molecular Weight: 57745.4 Isoelectric Point: 8.6615 |
Chromosome | Chromosome/Scaffold: 3 Start: 29342992 End: 29344740 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 87 | 424 | 0 |
CAGRYIYMYDLPARFNADLVPAYQKHSPITDMSNDGLGSPITPDQDGAGFLPEKGAYDTDQHVLGMIFHARMKRYECLTHDPAAAAAVFVPFYAGFDASM RLWKTDLPERDALARDLVEWLTRRPEWRAMGGRDHFLVAGRVAWDFLRGKDDNGWGTTFLTFPAIRNTTVLSIEASPWVGHDFGVPYPSHFHPASDADVA AWQGRMRQAGRKWLWAFAGGPRPGSKKTVRAQIIQQCSDSSTCATFASATGHHNSPGRIMALLESARFCLQPCGDSFTRKSTFDAILAGCIPVYFHPLSA YVQYTWHLPRDYRSYSVFIPQADVARRNVSIEDVLRKI |
Full Sequence |
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Protein Sequence Length: 515 Download |
MKPCSVPTIE RYAAGDNGDS KHPNKGDGAG LLIRPSRLFY LTVLSTAFWT LVFYFNSTAQ 60 GNVASTVLFK RSAFSLPSSF RFVRDRCAGR YIYMYDLPAR FNADLVPAYQ KHSPITDMSN 120 DGLGSPITPD QDGAGFLPEK GAYDTDQHVL GMIFHARMKR YECLTHDPAA AAAVFVPFYA 180 GFDASMRLWK TDLPERDALA RDLVEWLTRR PEWRAMGGRD HFLVAGRVAW DFLRGKDDNG 240 WGTTFLTFPA IRNTTVLSIE ASPWVGHDFG VPYPSHFHPA SDADVAAWQG RMRQAGRKWL 300 WAFAGGPRPG SKKTVRAQII QQCSDSSTCA TFASATGHHN SPGRIMALLE SARFCLQPCG 360 DSFTRKSTFD AILAGCIPVY FHPLSAYVQY TWHLPRDYRS YSVFIPQADV ARRNVSIEDV 420 LRKIPPAQVA RMREEVIRLI PRVMYRDPTA KDTSFKDAFD VAVDAVVHRV AKRRRAAAEG 480 REYVDSVDGN DSWKYDLLED GQNHVGPHEF DPYM* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-60 | 86 | 424 | 355 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACY08857.1 | 0 | 85 | 513 | 155 | 587 | xyloglucan galactosyltransferase [Eucalyptus grandis] |
GenBank | EAZ16326.1 | 0 | 24 | 514 | 8 | 472 | hypothetical protein OsJ_31788 [Oryza sativa Japonica Group] |
GenBank | EEC67105.1 | 0 | 24 | 514 | 127 | 625 | hypothetical protein OsI_33901 [Oryza sativa Indica Group] |
RefSeq | NP_001064768.1 | 0 | 24 | 514 | 8 | 506 | Os10g0458900 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002468517.1 | 0 | 85 | 513 | 137 | 568 | hypothetical protein SORBIDRAFT_01g047270 [Sorghum bicolor] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EG375845 | 253 | 213 | 456 | 0 |
EE075461 | 249 | 196 | 441 | 0 |
CX076275 | 261 | 160 | 417 | 0 |
FL739554 | 250 | 196 | 442 | 0 |
JG636298 | 264 | 157 | 417 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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