Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10025252m |
Family | GT47 |
Protein Properties | Length: 505 Molecular Weight: 58441.2 Isoelectric Point: 7.4002 |
Chromosome | Chromosome/Scaffold: 4 Start: 8690786 End: 8692300 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 83 | 425 | 0 |
CAGRYIYMHNLPSIFNDDIIKDCRPLIKWFDMCPFMVNSGLGPQVSDSDNTTARVLTVETGSWYSTNQFLLAVIFRERMKHYECLTNDSSLASAVYVPFY AGFDVSRHLWGYNMTVRDELGIKLARWLREKPEWGKMHGRDHFFVTGRIAWDFRRVRDEDSDWGNKLMRLPEFANMTMLAIETTAWANEFAVPYPTYFHP KSLNEIWRWQRKVKSLKREYLFSFVGGPRPNLDGSIRGEIIKQCLASQGNCKFLNCNVNDCDNPVKIMEVFENSVFCLQPSGDSYTRRSIFDSILAGCIP VFFSPGSGYNQYIWYFPKDYTKYSVYIPEKEMRNGTFSLNKFL |
Full Sequence |
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Protein Sequence Length: 505 Download |
MMKQVPRIWV VILVTFVFCL FVLFQINKID LIETNLQITH QVNNFFISIA ASSHNQTLSF 60 TRNANESDGI RAKQPEEEDT DACAGRYIYM HNLPSIFNDD IIKDCRPLIK WFDMCPFMVN 120 SGLGPQVSDS DNTTARVLTV ETGSWYSTNQ FLLAVIFRER MKHYECLTND SSLASAVYVP 180 FYAGFDVSRH LWGYNMTVRD ELGIKLARWL REKPEWGKMH GRDHFFVTGR IAWDFRRVRD 240 EDSDWGNKLM RLPEFANMTM LAIETTAWAN EFAVPYPTYF HPKSLNEIWR WQRKVKSLKR 300 EYLFSFVGGP RPNLDGSIRG EIIKQCLASQ GNCKFLNCNV NDCDNPVKIM EVFENSVFCL 360 QPSGDSYTRR SIFDSILAGC IPVFFSPGSG YNQYIWYFPK DYTKYSVYIP EKEMRNGTFS 420 LNKFLGGIDM ESISRMRNEV AKIIPKIIYT KPGLVGPEKI EDAFEIAVDR TLERVAMVKR 480 MMEEGKDLQS EYSPIKDLKK LEVM* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-66 | 82 | 414 | 347 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_180833.1 | 0 | 80 | 479 | 63 | 464 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_180834.1 | 0 | 1 | 504 | 1 | 504 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002321098.1 | 0 | 43 | 487 | 16 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518606.1 | 0 | 80 | 487 | 73 | 472 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002532518.1 | 0 | 7 | 487 | 13 | 506 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |