Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 28455.m000369 |
Family | GT47 |
Protein Properties | Length: 456 Molecular Weight: 52469.3 Isoelectric Point: 7.3019 |
Chromosome | Chromosome/Scaffold: 28455 Start: 173256 End: 174626 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 37 | 395 | 0 |
CTNRWIHIRKLPPRFNLDLLSNCSEYPLFDNFCPFLANHGLGPKTHNRSQSWYRSDPLLLEVTFHRRMLEYPCLTSDPNLANAIYLPYYAAIDSLRYLYG PEVNNSMDHGLELFDFLQENDLKIWEKYNGMDHFLVMARPAWDFSQPLDANPPVWGTSFLELPEFFNVTALVIESRARPWQEQAVPYLTSFHPPTLALLE SWIKRVKGSRRTTLMLFAGGGGVGATPNIRRSIRNECENSSDSNTSGSFLGSFGYSYLHYTKVCDLVDCSNGICEHDPIRYMRPMLQATFCLQPPGDTPT RRSTFDAIIAGCIPVFFEEQTAKLQYGWHLPEEMHEEFAVFIPKEEVVFKGLKILDVLM |
Full Sequence |
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Protein Sequence Length: 456 Download |
MACKVQFFLH FYFLFITIIN QTFCQEANPE PKTLTDCTNR WIHIRKLPPR FNLDLLSNCS 60 EYPLFDNFCP FLANHGLGPK THNRSQSWYR SDPLLLEVTF HRRMLEYPCL TSDPNLANAI 120 YLPYYAAIDS LRYLYGPEVN NSMDHGLELF DFLQENDLKI WEKYNGMDHF LVMARPAWDF 180 SQPLDANPPV WGTSFLELPE FFNVTALVIE SRARPWQEQA VPYLTSFHPP TLALLESWIK 240 RVKGSRRTTL MLFAGGGGVG ATPNIRRSIR NECENSSDSN TSGSFLGSFG YSYLHYTKVC 300 DLVDCSNGIC EHDPIRYMRP MLQATFCLQP PGDTPTRRST FDAIIAGCIP VFFEEQTAKL 360 QYGWHLPEEM HEEFAVFIPK EEVVFKGLKI LDVLMGIPRA QVRRMREKVI ELMPRIVYRK 420 HGSSLGLRAK KDAFDIAVEG ALQRINSRLK GGSLYQ |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-47 | 37 | 384 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 35 | 449 | 35 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 36 | 454 | 32 | 443 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 33 | 449 | 25 | 429 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 1 | 456 | 1 | 439 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 1 | 456 | 1 | 456 | catalytic, putative [Ricinus communis] |