Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr3g084400.1 |
Family | GT47 |
Protein Properties | Length: 485 Molecular Weight: 56573.7 Isoelectric Point: 7.841 |
Chromosome | Chromosome/Scaffold: 3 Start: 27377797 End: 27379251 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 63 | 410 | 0 |
SCTGRYVFIQNLPSRFNQYLLQNCQFLTRGTDKPNMCPYMDNMGLGPEVKNQNFKDILVPNNTWYATNQFLLEVIFHNRMKSYECLTNDSSLASAVFVPS YIGLDISRFLWVNNLTVRDSSGFELVNWLVEKPEWKKMWGRDHFLISGRISWDFRRQFDDLAYWGSKFRFLPQSMNMSMLAVEGSSWNNDYAIPYPTSFH PSMDNDVLQWQSKIRHQKREFLFTFTGAPRPENEDSIRGKIIEQCRGSRFCKFIDCSYGGEKCDDPVNVMKVFGNSVFSLQPSGDSYTRRSIFDSILAGC IPVFFHPGTAYSQYKWHLPRNRTKYSVYIPVKDVKEWNVDLEKVLLEI |
Full Sequence |
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Protein Sequence Length: 485 Download |
MEKTPMISRS CNNHHQLWFA ILISFLLCSL LVLCFDYSHT FQTPNNILNF SLNKKPNTFV 60 SDSCTGRYVF IQNLPSRFNQ YLLQNCQFLT RGTDKPNMCP YMDNMGLGPE VKNQNFKDIL 120 VPNNTWYATN QFLLEVIFHN RMKSYECLTN DSSLASAVFV PSYIGLDISR FLWVNNLTVR 180 DSSGFELVNW LVEKPEWKKM WGRDHFLISG RISWDFRRQF DDLAYWGSKF RFLPQSMNMS 240 MLAVEGSSWN NDYAIPYPTS FHPSMDNDVL QWQSKIRHQK REFLFTFTGA PRPENEDSIR 300 GKIIEQCRGS RFCKFIDCSY GGEKCDDPVN VMKVFGNSVF SLQPSGDSYT RRSIFDSILA 360 GCIPVFFHPG TAYSQYKWHL PRNRTKYSVY IPVKDVKEWN VDLEKVLLEI PEKEVIAMRE 420 EVIKLIPKIV YADPRSKLDN FEDAFDLALK GMLERIENVR ETMRKGKDPS VGFADEDHYK 480 YTFN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-61 | 63 | 410 | 363 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAB10178.1 | 0 | 17 | 484 | 23 | 473 | hypothetical protein [Arabidopsis thaliana] |
RefSeq | NP_193135.2 | 0 | 17 | 484 | 31 | 512 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002300146.1 | 0 | 1 | 484 | 6 | 513 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518609.1 | 0 | 7 | 475 | 1 | 482 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002532518.1 | 0 | 1 | 484 | 1 | 522 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |