Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 487999 |
Family | GT47 |
Protein Properties | Length: 547 Molecular Weight: 63404 Isoelectric Point: 9.8502 |
Chromosome | Chromosome/Scaffold: 6 Start: 4687629 End: 4695918 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 218 | 498 | 0 |
QTLKVYIYSEGDRPIFHQPEAIMEGIYASEGWFMKLMESNHRFLTKDPNIAHLFYLPFSTRILQQKLYVHDSHSRRNLVKYLKNYLDLIASNYPFWNRTR GSDHFFTACHDWAPAETRGPYINCIRSLCNADVGVDFVVGKDVSLPETKISSSQNPNGNIGGNRPSKRTILAFFAGNLHGYVRPILLNQWSSRPEPDMKI FNRIDHKSYIRYMKRSRFCVCAKGYEVNSPRVVESVLYGCVPVIISDNFVPPFLEILNWESFAVFVPEKEIPNLRKILISI |
Full Sequence |
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Protein Sequence Length: 547 Download |
MDRSRVLRFL SQVETCRVVL LMVLVVAFVS GLQYFELAPV LSIVSPGNGT VSEYRESNDT 60 TKSTENETFL ASQEASTELK PYNNITSEVL KSSEHKFLND SPKIEASGQS RRSNETASSL 120 HSLQPRIPQI HKKYPHRSTK KPPVVVISIT QMNKMILKRH NDPKNSLAPR WGLKVDEELR 180 TARDKIKNVG LLKKDDNLYA PLYHNLSIFK RSYELMEQTL KVYIYSEGDR PIFHQPEAIM 240 EGIYASEGWF MKLMESNHRF LTKDPNIAHL FYLPFSTRIL QQKLYVHDSH SRRNLVKYLK 300 NYLDLIASNY PFWNRTRGSD HFFTACHDWA PAETRGPYIN CIRSLCNADV GVDFVVGKDV 360 SLPETKISSS QNPNGNIGGN RPSKRTILAF FAGNLHGYVR PILLNQWSSR PEPDMKIFNR 420 IDHKSYIRYM KRSRFCVCAK GYEVNSPRVV ESVLYGCVPV IISDNFVPPF LEILNWESFA 480 VFVPEKEIPN LRKILISIPV RRYVEMQKRV MKVQKHFMWH DGEPVRYDVF HMILHSVWYN 540 RVFQTF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-61 | 220 | 498 | 299 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42362.1 | 0 | 1 | 546 | 1 | 546 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_196722.1 | 0 | 1 | 546 | 1 | 546 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_974766.1 | 0 | 1 | 444 | 1 | 444 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002309547.1 | 0 | 99 | 544 | 24 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 142 | 545 | 51 | 453 | catalytic, putative [Ricinus communis] |