Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a024162m |
Family | GT47 |
Protein Properties | Length: 399 Molecular Weight: 45838.6 Isoelectric Point: 9.4537 |
Chromosome | Chromosome/Scaffold: 79 Start: 123259 End: 125679 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 66 | 350 | 0 |
EKRFKVYVYEEGELPIVHDGPCKDIYTSEGRFIHEMEHGNNRFRTNNPRAAHVYFMPFSVTWMVKYLYTPDTYNLTPLKQFVSDYVKLISVKHPFWNTTQ GADHFMLSCHDWAPHASRGNSFLYNTSIRVLCNANSSEGFNPQKDVSLPEIHLYGGNVNPKLISPPPSNLSRPFLAFFAGGLHGPIRSILLQHWKGRDSD LRIYEYLPKDQDYYDSMLWSKFCLCPSGYEVASPRIVEAVYAECIPVILSDHYVLPFSDVLKWEAFSIQVDISEIPRLKEILLGV |
Full Sequence |
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Protein Sequence Length: 399 Download |
MQRRANSNNK KEQGLAKSRA AIRKAASNRN LSSAIININS NGSSILSSST IYRNPTAFFQ 60 SYKEMEKRFK VYVYEEGELP IVHDGPCKDI YTSEGRFIHE MEHGNNRFRT NNPRAAHVYF 120 MPFSVTWMVK YLYTPDTYNL TPLKQFVSDY VKLISVKHPF WNTTQGADHF MLSCHDWAPH 180 ASRGNSFLYN TSIRVLCNAN SSEGFNPQKD VSLPEIHLYG GNVNPKLISP PPSNLSRPFL 240 AFFAGGLHGP IRSILLQHWK GRDSDLRIYE YLPKDQDYYD SMLWSKFCLC PSGYEVASPR 300 IVEAVYAECI PVILSDHYVL PFSDVLKWEA FSIQVDISEI PRLKEILLGV SEDKYLMLKE 360 GLRAVRKHFV LNQPVKKFDV FHMILHSVWL RRLNLRVG* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-63 | 65 | 350 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 11 | 398 | 94 | 478 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 4 | 397 | 94 | 479 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 65 | 398 | 1 | 334 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 65 | 397 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 12 | 398 | 104 | 481 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
FE523338 | 281 | 52 | 331 | 0 |
DR923559 | 239 | 161 | 399 | 0 |
GE475605 | 293 | 108 | 398 | 0 |
GW864815 | 308 | 81 | 387 | 0 |
GO363500 | 280 | 93 | 371 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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