Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_020_00041.1 |
Family | GT47 |
Protein Properties | Length: 491 Molecular Weight: 56117.7 Isoelectric Point: 8.3469 |
Chromosome | Chromosome/Scaffold: 20 Start: 334275 End: 337401 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 158 | 441 | 0 |
EKRFRVWAYKEGEPPLVHDGPVNNIYSTEGQFIDEMDSGKNPLMAKHPDEAHAFFLPFSVANVIRYVYKPERSFNRDRLQLLVEDYVSVIANKYPYWNRS SGADHFMVSCHDWAPDINDAHPELFQHFIRVLCNANASEGFQAWRDVSLPEIYLPFGRLGAPNLAKPVSKRSLLAFFAGGNHGHIRKKLLKLWKGKDNDV QVHEYLPKGLNYTQMMGQSKYCLCPSGWEVASPRVVEAIQAGCVPVILSEDYVLPFSDVLDWSQFSVQIPVEKIPEIKIILQEI |
Full Sequence |
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Protein Sequence Length: 491 Download |
MLLLFVYFST FSYKQHLITT TTTTTTFSSQ NITTTHLSST SFSNITSTSI NISSTEDISS 60 NSSQSSDDFY NGFFSFNSSN LNTTTTNTTG DIIPANKPLI REKSSLERIE DGLARARTAI 120 REAVRTCNYT SHKDEDFIPR GSVYRNPYAF HQSHIEMEKR FRVWAYKEGE PPLVHDGPVN 180 NIYSTEGQFI DEMDSGKNPL MAKHPDEAHA FFLPFSVANV IRYVYKPERS FNRDRLQLLV 240 EDYVSVIANK YPYWNRSSGA DHFMVSCHDW APDINDAHPE LFQHFIRVLC NANASEGFQA 300 WRDVSLPEIY LPFGRLGAPN LAKPVSKRSL LAFFAGGNHG HIRKKLLKLW KGKDNDVQVH 360 EYLPKGLNYT QMMGQSKYCL CPSGWEVASP RVVEAIQAGC VPVILSEDYV LPFSDVLDWS 420 QFSVQIPVEK IPEIKIILQE IPNDKYLQLQ KRVLRVQKHF VVNRPAKRFD VMHMVLHSVW 480 LRRLNLRLPS * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-56 | 157 | 441 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03873.1 | 0 | 96 | 488 | 227 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 100 | 489 | 9 | 401 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 100 | 489 | 82 | 476 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 100 | 489 | 1 | 395 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002515488.1 | 0 | 70 | 488 | 40 | 468 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC939466 | 295 | 100 | 389 | 0 |
JG591774 | 219 | 101 | 319 | 0 |
FD507587 | 224 | 202 | 425 | 0 |
FE523338 | 288 | 135 | 417 | 0 |
GE475605 | 297 | 195 | 488 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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