Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 872147 |
Family | GT47 |
Protein Properties | Length: 471 Molecular Weight: 54690.1 Isoelectric Point: 8.4875 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 141 | 422 | 0 |
RMFKIYVYEEGDPPIFHYGLCKDIYSMEGLFLNFMENDVLKYRTRDPDKAHVYFLPFSVVMILHHLFDPVVRDKAVLESVIADYVQIISKKYPYWNTSDG FDHFMLSCHDWGHRATWYVKKLFFNSIRVLCNANISEYFNPEKDAPFPEINLLTGEINNLTGGLDPISRKTLAFFAGKSHGKIRPVLLNHWKEKDKDILV YENLPEDLNYTEMMRKTRFCICPSGHEVASPRIPEAIYSGCVPVLISENYVLPFSDVLNWEKFSVSVSVKEIPELKRILMDI |
Full Sequence |
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Protein Sequence Length: 471 Download |
MRDYIPKYLN AFLLAFATFA VVFAIFIAKD SNSSSHLYFS TSSSLWTSSF SSAFITVTIF 60 LSVHRFREKR KRNGSNPGSG YWKRDGKVEA ELATARALIR EAQLNSNSTA SSPLGDEDYV 120 PHGDIYRNPY AFHRSYLLME RMFKIYVYEE GDPPIFHYGL CKDIYSMEGL FLNFMENDVL 180 KYRTRDPDKA HVYFLPFSVV MILHHLFDPV VRDKAVLESV IADYVQIISK KYPYWNTSDG 240 FDHFMLSCHD WGHRATWYVK KLFFNSIRVL CNANISEYFN PEKDAPFPEI NLLTGEINNL 300 TGGLDPISRK TLAFFAGKSH GKIRPVLLNH WKEKDKDILV YENLPEDLNY TEMMRKTRFC 360 ICPSGHEVAS PRIPEAIYSG CVPVLISENY VLPFSDVLNW EKFSVSVSVK EIPELKRILM 420 DIPEERYMRL YEGVKKVKMH ILVNDPPKRY DVFNMIIHSI WLRRLNVKLL * 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-65 | 143 | 422 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI28482.1 | 0 | 70 | 469 | 226 | 634 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_187419.1 | 0 | 1 | 470 | 1 | 470 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002264111.1 | 0 | 139 | 469 | 1 | 330 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002320537.1 | 0 | 87 | 469 | 13 | 393 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524592.1 | 0 | 87 | 470 | 6 | 387 | catalytic, putative [Ricinus communis] |