Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra006550 |
Family | GT47 |
Protein Properties | Length: 394 Molecular Weight: 45104.6 Isoelectric Point: 10.2331 |
Chromosome | Chromosome/Scaffold: 03 Start: 4000389 End: 4005339 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 116 | 344 | 0 |
FHHVANVVEYLYHPLVTYSREQLHKVFLDYVSVVTHKYPYWNRSLGADHFFVSCHDWAPEVSGSDPELLKNMIRVLCNANTSEGFMPQRDVSIPEINIPL GQLGPPRLSNSSGHDRPILAFFAGRVHGNIRKILLQHWKDKDDEVQVHEYLPRKEDYFKLMAKARFCLCPSGYEVASPRVVATISLGCVPVIISDHYALP FSDVLDWSKFTIHVPSEKIPEIKTILKSV |
Full Sequence |
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Protein Sequence Length: 394 Download |
MKFSLATALL LLIILLFYQH LSSLNLNLIT LSSLSHATSL APSPSPSMSM EFSILSSNVT 60 LTPGAQKKEK KRNRIEKGLA KSRAAIREAM TSKKYAFEKE KTFVPRGTVY RNAYAFHHVA 120 NVVEYLYHPL VTYSREQLHK VFLDYVSVVT HKYPYWNRSL GADHFFVSCH DWAPEVSGSD 180 PELLKNMIRV LCNANTSEGF MPQRDVSIPE INIPLGQLGP PRLSNSSGHD RPILAFFAGR 240 VHGNIRKILL QHWKDKDDEV QVHEYLPRKE DYFKLMAKAR FCLCPSGYEV ASPRVVATIS 300 LGCVPVIISD HYALPFSDVL DWSKFTIHVP SEKIPEIKTI LKSVSLRRYK VLQRRVLQVQ 360 RHFVINRPSQ PFDMLRMILH SVWLRRLNMR VHV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam13692 | Glyco_trans_1_4 | 0.007 | 264 | 322 | 60 | + Glycosyl transferases group 1. | ||
pfam03016 | Exostosin | 4.0e-51 | 125 | 344 | 235 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_197526.4 | 0 | 50 | 391 | 1 | 407 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 17 | 391 | 26 | 465 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002324625.1 | 0 | 119 | 391 | 61 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331029.1 | 0 | 119 | 391 | 61 | 334 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531945.1 | 0 | 1 | 391 | 5 | 450 | catalytic, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2jhp_A | 0.002 | 231 | 320 | 367 | 457 | A Chain A, Crystal Structure Of Class V Chitinase From Nicotiana Tobaccum |
PDB | 2jhc_A | 0.002 | 231 | 320 | 367 | 457 | A Chain A, Crystal Structure Of Class V Chitinase From Nicotiana Tobaccum |
PDB | 2jha_A | 0.002 | 231 | 320 | 367 | 457 | A Chain A, Crystal Structure Of Class V Chitinase From Nicotiana Tobaccum |
PDB | 2jh9_A | 0.002 | 231 | 320 | 367 | 457 | A Chain A, Crystal Structure Of Class V Chitinase From Nicotiana Tobaccum |
PDB | 2jh8_A | 0.002 | 231 | 320 | 367 | 457 | A Chain A, The Structure Of Bluetongue Virus Vp4 Reveals A Multifunctional Rna-capping Production-line |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |