Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10002799 |
Family | GT47 |
Protein Properties | Length: 627 Molecular Weight: 71029.5 Isoelectric Point: 9.057 |
Chromosome | Chromosome/Scaffold: 668 Start: 24439 End: 26585 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 299 | 580 | 0 |
NMLKVYVYREGERPVFHQPALRGIYASEGWFMRQMESYKKFVTRDSRKAHLFYLPFGSRNLEEAMYVPNSHSHKNLIQYLKDYLDMVSAKHPFWNRTDGA DHFLVACHDWAPAETRQYMSNSIRALCNADVKEGFVFGKDSSLPETNVRNPQKPLRDIGGQSASKRSILAFYAGNMHGYVRPILLQHWQNKDPDIKVYGV MPKSKGNKNYIQHMRSSKYCICPKGYEVNSPRVVEAIFHECVPVIISDNFVPPFFEVLNWESFAVFVLEKDIPNLKNILLSI |
Full Sequence |
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Protein Sequence Length: 627 Download |
MGQEIGLRCQ GESWKLLSLV AITFALAVTF QYIELPYATF WPSTTSSTAK AIVDPEAKGL 60 NDSFPFVLEH RNNSSNVEAA DDGDPEDRTE NLGKDFVSQG VNKSSGSSDQ ELLLTNNSNS 120 TLLPKNSSAD NASDVSFAPQ TEGSSVVEPP KESSNNISST IPKIADANAP NRAASVDSMK 180 PANTNQGSNN GKSDKLQTDI SNADANPSPK KVAEKRRKPS DATIIPAVLT ISEMNRLMLQ 240 SWTAPHVINP RWPSAADQQL RHARSEIEHA PVTANDPILY APIYRNVSMF KRSYELMENM 300 LKVYVYREGE RPVFHQPALR GIYASEGWFM RQMESYKKFV TRDSRKAHLF YLPFGSRNLE 360 EAMYVPNSHS HKNLIQYLKD YLDMVSAKHP FWNRTDGADH FLVACHDWAP AETRQYMSNS 420 IRALCNADVK EGFVFGKDSS LPETNVRNPQ KPLRDIGGQS ASKRSILAFY AGNMHGYVRP 480 ILLQHWQNKD PDIKVYGVMP KSKGNKNYIQ HMRSSKYCIC PKGYEVNSPR VVEAIFHECV 540 PVIISDNFVP PFFEVLNWES FAVFVLEKDI PNLKNILLSI SQRRYLQMQM RVKRVQQHFL 600 WHPKPVKYDV FHMILHSIWY NRVFRT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-70 | 301 | 580 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 185 | 625 | 140 | 592 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 12 | 625 | 12 | 651 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 625 | 1 | 665 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 189 | 625 | 31 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 234 | 626 | 1 | 395 | predicted protein [Populus trichocarpa] |