Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10003620m |
Family | GT47 |
Protein Properties | Length: 492 Molecular Weight: 56604.6 Isoelectric Point: 7.3768 |
Chromosome | Chromosome/Scaffold: 6 Start: 3511577 End: 3513886 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 157 | 440 | 0 |
EKRFKIWTYREGEAPLFHKGPLNNIYAIEGQFMDEIENGDSRFKAASPEEATVFYIPVGIVNIIRFVYRPYTSYARDRLQNVVKDYISLVSNRYPYWNRS HGADHFFLSCHDWAPDVSAADPELYRHFIRALCNANASEGFTPMRDVSLPEINIPQSQLGYVHTGEQPQNRKLLAFFAGGSHGEVRKILFDQWKEKDKDV QVYEYLPKTINYTKMMDKAKFCLCPSGWEVASPRIVESLYSGCVPVIIADSYVLPFSDVLNWKAFSIHIPISKIPEIKKILEAI |
Full Sequence |
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Protein Sequence Length: 492 Download |
MADLTCTTPF LLYPSLVIIL FFYSINNHEQ IFSSSVIDYD DPSCRRLSSP PQQQQQRAGF 60 SSLRIFPFRS PPSCLNTTSN TNLTATSEVV VVKELVDEAV ERIEEGLAMA RAAIRKAGEE 120 SLRRDRDRTN NSDTGFVSNG SVYLNAFTFH QSHREMEKRF KIWTYREGEA PLFHKGPLNN 180 IYAIEGQFMD EIENGDSRFK AASPEEATVF YIPVGIVNII RFVYRPYTSY ARDRLQNVVK 240 DYISLVSNRY PYWNRSHGAD HFFLSCHDWA PDVSAADPEL YRHFIRALCN ANASEGFTPM 300 RDVSLPEINI PQSQLGYVHT GEQPQNRKLL AFFAGGSHGE VRKILFDQWK EKDKDVQVYE 360 YLPKTINYTK MMDKAKFCLC PSGWEVASPR IVESLYSGCV PVIIADSYVL PFSDVLNWKA 420 FSIHIPISKI PEIKKILEAI PEEEYLELQR KVLEVRKHFV VNRPSKPYDM LHMIMHSIWL 480 RRLNVRIPLS Q* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-59 | 156 | 421 | 284 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21065.1 | 0 | 101 | 489 | 16 | 402 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25529.1 | 0 | 100 | 487 | 4 | 386 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_196674.1 | 0 | 156 | 491 | 1 | 336 | exostosin family protein [Arabidopsis thaliana] |
Swiss-Prot | Q9LFP3 | 0 | 1 | 491 | 1 | 480 | GLYT4_ARATH RecName: Full=Probable glycosyltransferase At5g11130 |
RefSeq | XP_002515488.1 | 0 | 1 | 487 | 12 | 468 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC939466 | 265 | 129 | 388 | 0 |
FE523338 | 291 | 132 | 421 | 0 |
GE475605 | 295 | 196 | 487 | 0 |
FD507587 | 223 | 199 | 421 | 0 |
JK524792 | 253 | 139 | 388 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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